Extensive Keratinized Tissue Augmentation During Implant Rehabilitation After Le Fort I Osteotomy

Abstract

The aim of this study was to test a new collagen matrix (Mucoderm) positioned during oral implant abutment connection. A patient previously treated with Le Fort I for bone augmentation and 8 implants showing minimal amount of keratinized tissue was selected for an extensive keratinized tissue augmentation and deepening of the oral vestibule by apically positioning a split palatal flap and palatal grafting with Mucoderm. Clinical data at 9 and 14 days and 1 and 2 months showed resorption of the collagen graft, augmentation of the keratinized tissue around the implants, and deepening of the vestibule, with minimal morbidity and reduced surgical treatment time. However, some vestibular keratinized tissue contraction was evident. The new collagen matrix may be a promising material as a substitute for an autologous gingival/connective tissue graft. Despite the preliminary results of this innovative article, before drawing any general conclusion, the benefit of the procedure should be further evaluated by prospective clinical trials.

Soft tissue volume alterations after connective tissue grafting at teeth: the subepithelial autologous connective tissue graft versus a porcine collagen matrix – a pre‐clinical volumetric analysis

“…, Nocini et al. ). Originally, such collagen matrices were introduced to promote keratinized tissue regeneration and in the further course subsequently used for root coverage procedures (Sanz et al.…”

“…As alternative to SCTGs, xenogeneic soft tissue substitutes such as porcine-derived 3D collagen-based matrices are currently in the focus, with the intention to avoid postoperative patient morbidities and risks associated with autologous tissue grafting (Sanz et al 2009, Ghanaati et al 2011, Schmitt et al 2013, Nocini et al 2014. Originally, such collagen matrices were introduced to promote keratinized tissue regeneration and in the further course subsequently used for root coverage procedures (Sanz et al 2009, Herford et al 2010, McGuire & Scheyer 2010, Nevins et al 2011, Zuhr et al 2014.…”

Gingiva thickening with a porcine collagen matrix in a preclinical dog model: Histological outcomes

“…In clinical practice, the subepithelial connective tissue graft (SCTG) is regarded as the gold standard for such procedures (Jung, Siegenthaler, & Hammerle, 2004;Schwarz et al, 2014;Sculean et al, 2015;Thoma et al, 2014;Zuhr, Baumer, & Hurzeler, 2014). However, autologous tissue grafting is associated with postoperative patient morbidities and operative risks, motivating investigations of potential alternatives, such as porcine-derived 3D collagen-based matrices (Bassetti et al, 2016;Ghanaati et al, 2011;Nocini et al, 2014;Sanz, Lorenzo, Aranda, Martin, & Orsini, 2009;Schmitt et al, 2013).…”

Soft tissue augmentation applying a collagenated porcine dermal matrix during second stage surgery: A prospective multicenter case series

“…Therefore, current research focuses on alternative techniques and materials. A porcine acellular dermal collagen matrix (CM) has been introduced as an alternative to SCTGs in order to avoid surgical risks and to decrease patient morbidity . These matrices proved their ability to increase soft tissue thickness in preclinical animal studies .…”

“…A porcine acellular dermal collagen matrix (CM) has been introduced as an alternative to SCTGs in order to avoid surgical risks and to decrease patient morbidity. [15][16][17][18][19] These matrices proved their ability to increase soft tissue thickness in preclinical animal studies. [20][21][22] In a comparative dog study, a porcine CM has shown similar results as SCTG after a 10-month follow-up.…”