Extensive orbital inflammation in an anophthalmic socket: is the Bioceramic implant a bystander or a participant?

Cameron, Cassie; Tong, Jessica; Juniat, Valerie; Patel, Sandy; Dhatrak, Deepak; Selva, Dinesh

doi:10.1016/j.ajoc.2022.101721

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…Notably, a study of this material in 107 patients reported rare post-operative complications, with an implant exposure rate of only 9.1% [140]. However, recently Cameron and colleagues reported a case wherein a porous alumina implant wrapped in polyglactin 910 led to extensive orbital inflammation [141]. Research by Ramey and collaborators also found higher complication rates with alumina and porous PE than with HA implants [140,142,143].…”

Section: Ceramicsmentioning

confidence: 96%

The Use of Functional Biomaterials in Aesthetic and Functional Restoration in Orbital Surgery

Wu,

Fujioka,

Daigle

et al. 2024

JFB

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The integration of functional biomaterials in oculoplastic and orbital surgery is a pivotal area where material science and clinical practice converge. This review, encompassing primary research from 2015 to 2023, delves into the use of biomaterials in two key areas: the reconstruction of orbital floor fractures and the development of implants and prostheses for anophthalmic sockets post-eye removal. The discussion begins with an analysis of orbital floor injuries, including their pathophysiology and treatment modalities. It is noted that titanium mesh remains the gold standard for orbital floor repair due to its effectiveness. The review then examines the array of materials used for orbital implants and prostheses, highlighting the dependence on surgeon preference and experience, as there are currently no definitive guidelines. While recent innovations in biomaterials show promise, the review underscores the need for more clinical data before these new materials can be widely adopted in clinical settings. The review advocates for an interdisciplinary approach in orbital surgery, emphasizing patient-centered care and the potential of biomaterials to significantly enhance patient outcomes.

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Section: Ceramicsmentioning

confidence: 96%

The Use of Functional Biomaterials in Aesthetic and Functional Restoration in Orbital Surgery

Wu,

Fujioka,

Daigle

et al. 2024

JFB

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Interaction of Ceramic Implant Materials with Immune System

Rafikova

Piatnitskaia

Shapovalova

et al. 2023

IJMS

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The immuno-compatibility of implant materials is a key issue for both initial and long-term implant integration. Ceramic implants have several advantages that make them highly promising for long-term medical solutions. These beneficial characteristics include such things as the material availability, possibility to manufacture various shapes and surface structures, osteo-inductivity and osteo-conductivity, low level of corrosion and general biocompatibility. The immuno-compatibility of an implant essentially depends on the interaction with local resident immune cells and, first of all, macrophages. However, in the case of ceramics, these interactions are insufficiently understood and require intensive experimental examinations. Our review summarizes the state of the art in variants of ceramic implants: mechanical properties, different chemical modifications of the basic material, surface structures and modifications, implant shapes and porosity. We collected the available information about the interaction of ceramics with the immune system and highlighted the studies that reported ceramic-specific local or systemic effects on the immune system. We disclosed the gaps in knowledge and outlined the perspectives for the identification to ceramic-specific interactions with the immune system using advanced quantitative technologies. We discussed the approaches for ceramic implant modification and pointed out the need for data integration using mathematic modelling of the multiple ceramic implant characteristics and their contribution for long-term implant bio- and immuno-compatibility.

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A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures

Kulbay,

Wu,

Hocini

et al. 2024

Explor BioMat-X

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The fusion of biomaterial science with clinical practice in oculoplastic and orbital surgery, particularly in the reconstruction of the posterior lamella of the eyelid, the lacrimal system, orbital floor fractures, and the development of implants for anophthalmic sockets, represents a frontier where materials meet surgical techniques. This review, which spans research from 2015 to 2023, delves into the application and integration of biopolymers and functional biomaterials in these complex areas. The discussion begins by reviewing the key anatomy of the external ocular surface, lacrimal system, and orbit. It then summarizes the various current surgical approaches for treating diseases affecting the external ocular surface and orbital involvement, with an emphasis on the associated challenges. The discussion continues with a comprehensive overview of the advantages and disadvantages of current and emerging biomaterials, including synthetic and natural polymers, used in reconstructive surgeries. These include applications for eyelid structure reconstruction, lacrimal system repair, orbital bone fracture repair, and orbital socket reconstruction. Throughout the review, the pathophysiology and challenges associated with these reconstructive procedures are explored, with an emphasis on surgical nuances and the ongoing pursuit of optimal reconstruction techniques. Finally, this review serves as a valuable resource for familiarizing clinicians with current knowledge and generating future hypotheses. It concludes that no evidence-based guidelines currently exist in oculoplastic surgery regarding the use of biopolymers in reconstructive procedures. Further research is needed to evaluate the efficacy and reproducibility of these biopolymers.

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Extensive orbital inflammation in an anophthalmic socket: is the Bioceramic implant a bystander or a participant?

Cited by 3 publications

References 11 publications

The Use of Functional Biomaterials in Aesthetic and Functional Restoration in Orbital Surgery

The Use of Functional Biomaterials in Aesthetic and Functional Restoration in Orbital Surgery

Interaction of Ceramic Implant Materials with Immune System

A review of biopolymer innovations in oculoplastic surgery: reconstruction of eyelid, lacrimal, and orbital structures

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