External beam radiotherapy as postoperative treatment of diffuse pigmented villonodular synovitis

Radiation Therapy for Treatment of Pigmented Villonodular Synovitis: Results of a National Patterns of Care Study

“…Open or arthroscopic synovectomy (9,12,(16)(17)(18)(19)(20), external beam radiation therapy (RT) (21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39), and intra-articular radionuclid application (40)(41)(42)(43) have been shown to be effective for the primary treatment and the management of recurrent disease, either alone or in various combinations. Nevertheless, there is a wide consensus that surgical synovectomy and curettage of bony lesions is the treatment of choice for the primary management of PVNS (4).…”

Pigmented Villonodular Synovitis for Combined Therapy

“…No evidence of recurrence was found; one patient had persistent restriction of joint movement after surgery [11].…”

“…RT may be instituted either by external beam or through intra-articular injections (yttrium-90, rhenium-186) [11,25,26]. Initial and highly satisfactory experience with the injection of radioactive yttrium 90 to treat PVNS of the ankle joint eroded with time [27].…”

“…Several recent publications showed favorable effect of external beam RT as a postoperative treatment [11,12,18,[28][29][30][31]. The GCG-BD group conducted a pattern-of-care study to analyze the RT for PVNS [12].…”

“…3, left). Due to US data and high rate of PVNS relapse (8-56%) for 5 years [11], we made decision about external beam radiotherapy [12]. Photon beam irradiation (6 MV) through opposed anterior and posterior fields was given.…”