“…9,12,20,24,33,38 Short study time horizons and small sample sizes in the clinical studies in this field were also highlighted. 22,25,35,37,39,40 Moreover, for many of the studies, important outcomes, including quality of life, a full range of relevant costs, and long-term outcomes, were not collected, which may limit their ability to capture fully the value of these devices. 9,16,18,26,29,34,37,40 While few analysts gave specific reasons why such outcomes were not considered, it was noted across several studies that the summary benefit measure used (eg, fractures avoided) did not capture quality of life and, in some cases, there were inherent deficiencies in some of the measures used, such as clinical scoring and health-related quality of life instruments.…”