Extracorporeal membrane oxygenation (ECMO) for near-fatal asthma refractory to conventional ventilation

Maqsood, Usman; Patel, Nehal

doi:10.1136/bcr-2017-223276

Cited by 11 publications

(6 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…VV and veno-arterial ECMO are now increasingly used for acute respiratory distress syndrome and refractory cardiogenic shock, respectively, but also for nontraditional indications such as upper airway surgery, 2 pulmonary embolism, 3 and malignant airway obstructions. 4 There are several case reports of VV ECMO utilization in refractory bronchospastic states like acute severe asthma [5][6][7][8] and anaphylaxis 9 for carbon dioxide removal. In our scenario, ECMO was a bridge to treat the patient's severe asthma exacerbation and tracheal stenosis.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of extracorporeal membrane oxygenation in status asthmaticus with severe tracheal stenosis

Odigwe

Krieg

Owens

et al. 2020

Baylor University Medical Center Proceedings

View full text Add to dashboard Cite

Extracorporeal membrane oxygenation, traditionally used to treat refractory hypoxemic respiratory failure due to acute respiratory distress syndrome, is being used to treat other etiologies of severe respiratory failure refractory to conventional mechanical ventilation. We present a 30-year-old woman with concomitant life-threatening airway obstruction due to severe tracheal stenosis and status asthmaticus treated effectively with veno-venous extracorporeal membrane oxygenation. KEYWORDS Acute severe asthma; extracorporeal membrane oxygenation; tracheal stenosisO bstruction of the central airways, the trachea and mainstem bronchi, can complicate many disease processes and in tracheal stenosis can be a complication of prior tracheostomy placement due to excess scar tissue formation. Asthma is an allergic condition characterized by bronchoconstriction with periods of exacerbation and remission. During severe exacerbations, patients may need mechanical ventilation. Severe asthma exacerbation in a patient with a compromised central airway due to tracheal stenosis can be challenging to manage. Veno-venous (VV) extracorporeal membrane oxygenation (ECMO) involves diversion of blood for extracorporeal oxygenation and carbon dioxide removal by an artificial "membrane lung" and is a salvage treatment for respiratory failure. There are reports of successful outcomes where VV ECMO has enabled performance of lifesaving procedures in high-risk patients with central airway obstruction. 1

show abstract

Section: Discussionmentioning

confidence: 99%

Usefulness of extracorporeal membrane oxygenation in status asthmaticus with severe tracheal stenosis

Odigwe

Krieg

Owens

et al. 2020

Baylor University Medical Center Proceedings

View full text Add to dashboard Cite

show abstract

“…Despite the survival benefit demonstrated above and in numerous case reports [123][124][125][126], high-quality comparative data to support ECMO use is limited. This owes to the rarity of ECMO use in near-fatal asthma and that it is not a standard feature in asthma guidelines [10].…”

Section: Ecmomentioning

confidence: 99%

Management of Acute Life-Threatening Asthma Exacerbations in the Intensive Care Unit

Talbot,

Roe,

Dushianthan

2024

Applied Sciences

View full text Add to dashboard Cite

Managing acute asthma exacerbations in critical care can be challenging and may lead to adverse outcomes. While standard management of an acute asthma exacerbation is well established in outpatient and emergency department settings, the management pathway for patients with life-threatening and near-fatal asthma still needs to be fully defined. The use of specific interventions such as intravenous ketamine, intravenous salbutamol, and intravenous methylxanthines, which are often used in combination to improve bronchodilation, remains a contentious issue. Additionally, although it is common in the intensive care unit setting, the use of non-invasive ventilation to avoid invasive mechanical ventilation needs further exploration. In this review, we aim to provide a comprehensive overview of the available treatments and the evidence for their use in intensive care. We highlight the ongoing need for multicentre trials to address clinical knowledge gaps and the development of intensive-care-based guidelines to provide an evidence-based approach to patient management.

show abstract

“…До настоящего времени идут поиски максимально эффективной и безопасной терапии лечения рефрактерного астматического статуса. Терапия включает применение миорелаксантов, гелия [75], общую анестезию севофлураном [76], ЭКМО [77][78][79]. Выбор режима ИВЛ остается дискутируемым вопросом.…”

Section: высокочастотная вентиляция с положительным давлением (Hfppv)unclassified

High-Frequency Ventilation in the Treatment of Acute Respiratory Failure

Перепелица

Александровна²,

Kuzovlev

et al. 2021

Physical and rehabilitation medicine, medical rehabilitation

View full text Add to dashboard Cite

The need for respiratory therapy can reach 90% depending on the category of the intensive care unit and intensive care unit (ICU). Currently is a wide selection of respiratory therapy methods, including fully controlled mechanical ventilation and assist ventilation. The widespread use of mechanical ventilation and its varieties significantly reduced the mortality of ICU patients. However, the mortality of patients from acute respiratory distress syndrome, nosocomial pneumonia, and newborns with respiratory disorders remains high. High-frequency mechanical ventilation (HFMV) is an alternative treatment for severe respiratory failure, but the frequency of use is not yet sufficient. Three main types of HF ventilation is currently available: high-frequency positive pressure ventilation (HFPPV), high-frequency jet ventilation (HFJV) and high-frequency oscillatory ventilation (HFOV). There is an opportunity to choose a specific mode which will be most applicable for a particular patient. The use of the HFOV method allows the successful treatment of newborns with severe respiratory failure due to primary surfactant deficiency, meconial aspiration or multiple organ failure. Recently high amount of publications appeared on the possibilities of non-invasive HFMV in both adult patients and in pediatrics. This mini-review is devoted to this problem.

show abstract

Extracorporeal membrane oxygenation (ECMO) for near-fatal asthma refractory to conventional ventilation

Cited by 11 publications

References 7 publications

Usefulness of extracorporeal membrane oxygenation in status asthmaticus with severe tracheal stenosis

Usefulness of extracorporeal membrane oxygenation in status asthmaticus with severe tracheal stenosis

Management of Acute Life-Threatening Asthma Exacerbations in the Intensive Care Unit

High-Frequency Ventilation in the Treatment of Acute Respiratory Failure

Contact Info

Product

Resources

About