Extracorporeal shock wave therapy as a bet for the treatment of burn patients

Cosmo, Alessio De; Maggio, Giulio; Tedeschi, Pasquale

doi:10.1016/j.burns.2021.04.027

Cited by 3 publications

(2 citation statements)

References 4 publications

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“… Wound Healing . ① Wound healing time: the time from being injured to complete epithelization of wound; ② wound healing rate: mean wound healing rate = (wound area immediately after injury − wound area at each time phase)/wound area immediately after injury × 100%; ③ wound healing quality: the Vancouver scar scale (VSS) [ 13 ] was used as the basis for evaluating the color, thickness, vascularity, softness of the scar area after the wound was healed, and on a scale of 0–15 points, higher scores indicated more serious scars. ARR .…”

Section: Methodsmentioning

confidence: 99%

Effect of Combining Immersion Therapy with Shengji Ointment on Wound Healing Rate and Adverse Reaction Rate in Patients with Second-Degree Burn

Guo

2021

Journal of Healthcare Engineering

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Objective. To explore the effect of combining immersion therapy with Shengji ointment on wound healing rate and adverse reaction rate (ARR) in patients with second-degree burn. Methods. The data of 80 patients with second-degree burn treated in our hospital from February 2019 to February 2020 were retrospectively analyzed by the means of retrospective study, and the patients were equally divided into the treatment group and the control group according to their admission order, with 40 cases each. Immersion therapy was performed to all patients (7 d); after that, patients in the control group received routine medication (7 d), and those in the treatment group were treated with Shengji ointment until the wounds were healed, so as to compare their wound healing condition, ARRs, levels of inflammatory factors, and infection incidence. Results. Compared with the control group after treatment, the treatment group presented significantly shorter wound healing time (12.14 ± 1.26 vs. 15.98 ± 1.20, P < 0.001), better wound healing rate and quality ( P < 0.05), and lower levels of inflammatory factors ( P < 0.001); no significant between-group difference in ARRs was shown ( P > 0.05); 34 patients in the treatment group (85.0%) and 26 patients in the control group (65.0%) had no infections, so the incidence rate of infections was significantly lower in the treatment group than in the control group (P < 0.05). Conclusion. Combining immersion therapy with Shengji ointment can reduce the levels of inflammatory factors in patients with second-degree burn, lower the incidence rate of infections, provide the conditions for wound healing, and increase the wound healing rate, which shall be promoted and applied in practice.

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Section: Methodsmentioning

confidence: 99%

Effect of Combining Immersion Therapy with Shengji Ointment on Wound Healing Rate and Adverse Reaction Rate in Patients with Second-Degree Burn

Guo

2021

Journal of Healthcare Engineering

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“…9,10 ESWT was originally developed for the treatment of urolithiasis in the 1980s and subsequently applied to treat various musculoskeletal disorders. 11 Recently, the application of ESWT has been expanded to the new therapeutic fields of regenerative medicine, 12 tissue engineering, 13 myocardial infarction, 14,15 erectile dysfunction, 16 acute and chronic wound, 17 burns 18 and its sequalae such as pathological scars and keloids after burns. 19,20 Several clinical studies demonstrated the efficacy of ESWT as a useful tool to treat PBPS.…”

Section: Introductionmentioning

confidence: 99%

Safety and efficacy of treating post‐burn pathological scars with extracorporeal shock wave therapy: A meta‐analysis of randomised controlled trials

Yang

Kang

Jiang

et al. 2022

Wound Repair Regeneration

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The clinical application of shockwave therapy has expanded to the treatment of pathological scars. The objective of this systematic review and meta‐analysis is to quantitatively evaluate the efficacy and safety of extracorporeal shockwave therapy combined with comprehensive rehabilitation therapy on post‐burn pathological scars compared to comprehensive rehabilitation therapy alone. The randomised controlled trials of extracorporeal shockwave therapy for post‐burn pathological scars published in English and Chinese languages before October 2021 were included. The methodological quality and risk of bias of the selected articles were assessed with the Cochrane Collaboration's ‘risk of bias’ tool. RevMan software was applied for data analysis. This is the first systematic review and meta‐analysis considering the effectiveness and safety of extracorporeal shockwave therapy on post‐burn pathological scars. And nine randomised controlled trials involving 422 patients were included in this meta‐analysis. The meta‐analysis results showed that, compared with comprehensive rehabilitation therapy alone, extracorporeal shockwave therapy combined with comprehensive rehabilitation therapy was more effective in relieving pain (standardized mean difference [SMD] = −0.59, 95% confidence interval [CI]: [−0.87 to −0.31], p < 0.0001) and pruritus related to pathological scars (SMD = −0.94; 95% CI: [−1.25 to −0.63], p = 0.004), improving scars' appearance (SMD = −1.78, 95% CI: [−3.37 to −0.19], p = 0.03) and elasticity (SMD = 0.25, 95% CI: [0.29–0.21], p < 0.00001), decreasing scars thickness (SMD = −0.13, 95% CI: [−0.25 to −0.01], p = 0.04) and promoting the maturation status of scars (SMD = −2.86, 95% CI: [−3.96 to −1.76], p < 0.00001). There were no reported serious adverse events during and after extracorporeal shockwave therapy in the included studies. Available data preliminarily suggested that the combination of extracorporeal shockwave therapy and comprehensive rehabilitation therapy had better therapeutic effect on post‐burn pathological scars than comprehensive rehabilitation therapy alone, without obvious side effects. However, further clinical well‐controlled randomised controlled trials are needed. Systematic review registration ID: PROSPERO CRD42022297573.

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Use of Integra dermal regeneration template in burn patients: An Italian expert consensus Delphi study

Giudice,

Ranno,

Lombardo

et al. 2024

Burns

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Extracorporeal shock wave therapy as a bet for the treatment of burn patients

Cited by 3 publications

References 4 publications

Effect of Combining Immersion Therapy with Shengji Ointment on Wound Healing Rate and Adverse Reaction Rate in Patients with Second-Degree Burn

Effect of Combining Immersion Therapy with Shengji Ointment on Wound Healing Rate and Adverse Reaction Rate in Patients with Second-Degree Burn

Safety and efficacy of treating post‐burn pathological scars with extracorporeal shock wave therapy: A meta‐analysis of randomised controlled trials

Use of Integra dermal regeneration template in burn patients: An Italian expert consensus Delphi study

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