Extraction, chemical characterization and antioxidant activity of Litchi chinensis Sonn. and Avena sativa L. seeds extracts obtained from pressurized n-butane

Paliga, Marshall; Novello, Zuleica; Dallago, Rogério Marcos; Scapinello, Jaqueline; Magro, Jacir Dal; Luccio, Marco Di; Tres, Marcus V.; Oliveira, J. Vladimir

doi:10.1007/s13197-016-2485-4

Cited by 15 publications

(6 citation statements)

References 21 publications

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“…The results revealed that the phytochemicals of litchi seed act as a strong antioxidant identical to ascorbic acid (Table 6). Paliga et al, 2017 andShukla et al, 2013 reported the antioxidant activity of litchi seed phytochemicals higher than 78.36%. Ibrahim and Mohamed, (2015) reviewed the chemical constituents and pharmacological activities of litchi seed, listing the single constituents known over the past few decades.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical characteristics and antioxidant potential of litchi chinensis sonn. seeds of bangladesh

Aktar

Islam

Raza

et al. 2022

Bangladesh J. Agri.

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Phytochemicals act against free radicals and are formed in human body continuously and damage body cells, causing many diseases like cellular damage, cancer, etc. Plant and their different parts are the main sources of phytochemicals. Litchi (Litchi chinensis Sonn.) is one of the most popular fruits of which only flesh is consumed by humans and the rest of the parts especially seeds are discarded. This study has been carried out to detect antioxidant potential in various extracts (aqueous and ethanol) of Bombay litchi variety seeds and to discover the contextual connection of phytochemicals as antioxidant activities. The collected seeds were washed, dried in sunlight, and finally ground to fine powder to a uniform particle size for extraction and isolation of phytochemicals. The qualitative and quantitative phytochemical analysis and antioxidant activities were determined using standard methods. Phytochemical screening reveals that most of the phytochemicals were extracted from litchi seed in ethanol. TPC and TFCs of ethanol extract were 19.86 and 20.60 mg/g, respectively. The antioxidant activity was estimated by DPPH assay method from litchi seed extracts, and IC50 of the seed phytochemicals and ascorbic acid was observed to be 274 and 240 μg/ml, respectively. On the other hand, free radical scavenging activities of seed phytochemicals were determined with ABTS assay; IC50 of seed phytochemicals and ascorbic acid was noted as 31 and 29 μg/ml, respectively. Results suggested that the litchi seed is one of the richest sources of phytochemicals that can be used as a source of bioactive compounds. It is concluded that bioactive litchi seed phytochemicals can be used as herbal medicine defense against aging, oxidative stress, cell damage as well as cancer. Bangladesh J. Agri. 2022, 47(1): 16-26

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Section: Discussionmentioning

confidence: 99%

Phytochemical characteristics and antioxidant potential of litchi chinensis sonn. seeds of bangladesh

Aktar

Islam

Raza

et al. 2022

Bangladesh J. Agri.

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“…He also found that EPC in the LS was 89.5 mg GAE/g extract and LS inhibited the DPPH radical with an IC 50 value of 0.65 mg/mL, demonstrating concentration-dependent antiradical action. However, Paliga et al [27] found that the EY of LS was around 3.5 wt%, total phenolic content of about 126.4 mg GAE/100 g and AOA of up to 78.36%. Similarly, Prasad et al [44] observed that maximum EY was found at 50% ethanol extract (26.8%), whereas 100% ethanol only produced 23.3%.…”

Section: Optimization Of Extraction Of Phenolic Compounds Using Rsmmentioning

confidence: 95%

“…Conventional and microwave extraction methods were used with different solvent such as distilled water, ethanol, citric acid, and baking soda. Paliga et al [27] investigated the effect of pressurized solvent (n-butane) on the extraction yield (EY), chemical composition and antioxidant activity (AOA) of LS extract using 7-100 bar and temperature in the range of 25 • C to 70 • C. Type and concentration of solvent, extraction temperature and time, solid-to-liquid ration, pressure, and pH may strongly affect the extraction process. It is necessary to optimize the extraction process before extraction of phenolic compounds [28].…”

Section: Introductionmentioning

confidence: 99%

Optimization of Ethanolic Extraction of Phenolic Antioxidants from Lychee and Longan Seeds Using Response Surface Methodology

Sai‐Ut

Kingwascharapong

Mazumder

et al. 2023

Foods

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Lychee seeds (LS) and longan seeds (LoS) are excellent sources of phenolic compounds (PCs) with strong antioxidant activity (AOA). The aim of this study was to optimize the extraction conditions regarding extraction yield (EY), extractable phenolic compound (EPC), and AOA from LS and LoS using surface response methodology (RSM). Solvent concentration, extraction temperature, time, and solid to liquid ratio were optimized using RSM. Increasing the solid to solvent ratio from 1:05 to 1:40 (w/v), increased EY for LoS, however, EY did not change from 1:20 to 1:40 for LS. Solid–liquid ratio 1:20 was chosen for this study. Increasing the quantity of solvent leads to higher EPC and FRAP. The results showed that LoS exhibited higher AOA than LS measured as DPPH, ABTS, and FRAP, respectively. Ethanol concentrations and temperatures significantly (p < 0.05) affect EY, EPC, and AOA. The results (R2 > 0.85) demonstrated a good fit to the suggested models and a strong correlation between the extraction conditions and the phenolic antioxidant responses. The ethanol concentrations of 41 and 53%, temperatures of 51 and 58 °C, and the corresponding times of 139 and 220 min were the optimal conditions that maximized the EY, EPC, and AOA from LS and LoS.

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“…In China, the seed of Litchi chinensis as TCMs is prescribed in many formulas for a long time owing to its great medicinal value [338]. The chemical studies show that the components in the seed of Litchi chinensis mainly are polyphenols, such as rutin, gallic acid, procyanidin B2, gallocatechin, epicatechin, and epicatechin-3-gallate [339]. In our research group, a purified active fraction named lychee seed fraction enriching polyphenol (LSP) is obtained from lychee seed and its neuroprotective effect is investigated in multiple models of AD [340].…”

Section: Litchi Chinensismentioning

confidence: 99%

Dietary Plant Polyphenols as the Potential Drugs in Neurodegenerative Diseases: Current Evidence, Advances, and Opportunities

Guo

Zhang

et al. 2022

Oxidative Medicine and Cellular Longevity

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Neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), are characterized by the progressive degeneration of neurons. Although the etiology and pathogenesis of neurodegenerative diseases have been studied intensively, the mechanism is still in its infancy. In general, most neurodegenerative diseases share common molecular mechanisms, and multiple risks interact and promote the pathologic process of neurogenerative diseases. At present, most of the approved drugs only alleviate the clinical symptoms but fail to cure neurodegenerative diseases. Numerous studies indicate that dietary plant polyphenols are safe and exhibit potent neuroprotective effects in various neurodegenerative diseases. However, low bioavailability is the biggest obstacle for polyphenol that largely limits its adoption from evidence into clinical practice. In this review, we summarized the widely recognized mechanisms associated with neurodegenerative diseases, such as misfolded proteins, mitochondrial dysfunction, oxidative damage, and neuroinflammatory responses. In addition, we summarized the research advances about the neuroprotective effect of the most widely reported dietary plant polyphenols. Moreover, we discussed the current clinical study and application of polyphenols and the factors that result in low bioavailability, such as poor stability and low permeability across the blood-brain barrier (BBB). In the future, the improvement of absorption and stability, modification of structure and formulation, and the combination therapy will provide more opportunities from the laboratory into the clinic for polyphenols. Lastly, we hope that the present review will encourage further researches on natural dietary polyphenols in the treatment of neurodegenerative diseases.

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Extraction, chemical characterization and antioxidant activity of Litchi chinensis Sonn. and Avena sativa L. seeds extracts obtained from pressurized n-butane

Cited by 15 publications

References 21 publications

Phytochemical characteristics and antioxidant potential of litchi chinensis sonn. seeds of bangladesh

Phytochemical characteristics and antioxidant potential of litchi chinensis sonn. seeds of bangladesh

Optimization of Ethanolic Extraction of Phenolic Antioxidants from Lychee and Longan Seeds Using Response Surface Methodology

Dietary Plant Polyphenols as the Potential Drugs in Neurodegenerative Diseases: Current Evidence, Advances, and Opportunities

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