Extraction, Preconcentration and Isolation of Flavonoids from Apocynum venetum L. Leaves Using Ionic Liquid-Based Ultrasonic-Assisted Extraction Coupled with an Aqueous Biphasic System

Tan, Zhijian; Yi, Yanliang; Wang, Hongying; Zhou, Wanlai; Wang, Chaoyun

doi:10.3390/molecules21030262

Cited by 53 publications

(26 citation statements)

References 45 publications

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“…11 Ionic liquid are pure salt compound consisting of ionic components (cations and anions) that melt at a temperature below 100°C. 12 Application of ionic liquid increased total phenolic content and total flavonoid if compared to conventional solvent. 9 Tanshinone and crypto tanshinone were significantly extracted from Salvia miltiorrhiza Bunge by application of IL (C 14 mimBr and C 16 mimBr).…”

Section: Introductionmentioning

confidence: 98%

Enrichment of the Gamma Oryzanol Level from Rice Bran by Addition of Inorganic Salts on Ionic Liquid 1-Butyl-3- Methylimidazolium Hexafluorophosphate ([BMIM] PF6) Extraction

Trinovita

Sutriyo²,

Saputri³

et al. 2017

JYP

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Objective: Rice bran oil has many helath benefit. The biologically active compounds of rice bran oil are fatty acids, squalene, tocopherols, phytosterols, tocotrienols, oryzanol, and polyphenols. Gamma oryzanol is a combination of at least 10 components of ferulic acid esters and alcohols triterpene. Gamma oryzanol has pharmacological activity includes cardiovascular disease, antioxidant, anticancer, antidiabetic, antiulcerogenic, neuroprotective and action immunomodulator. Ionic liquids are an environmentally friendly solvent used in the extraction and separation of bioactive compounds from plants. This study was conducted to evaluate the effect of inorganic salts addition on ionic liquid [Bmim]PF 6 in increasing levels of gamma oryzanol from rice bran. Method: In the experiments, IL [Bmim]PF 6 -MAE method was used to separated gamma oryzanol compound, and then was partitioned with hexane after the addition of inorganic salts: KH 2 PO 4, NaCl, NaNO 3 and Na 2 CO 3 , respectively. Gamma oryzanol content was determined by HPLC analysis. A mixture of mobile phase (methanol:acetonitrile:isopropan ol (5:4:1) and isocratic conditions at a wavelength of 327 nm. The flow rate is set at 1 ml / min..Results: The highest levels of γ-oryzanol was produced from the addition in KH 2 PO 4 + : This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Section: Introductionmentioning

confidence: 98%

Enrichment of the Gamma Oryzanol Level from Rice Bran by Addition of Inorganic Salts on Ionic Liquid 1-Butyl-3- Methylimidazolium Hexafluorophosphate ([BMIM] PF6) Extraction

Trinovita

Sutriyo²,

Saputri³

et al. 2017

JYP

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“…Analysis of the mechanism extraction was performed with a comparison between morphological of before and after extraction process using Journal of Young Pharmacists, Vol 9, Issue 4, Oct-Dec, 2017 27 respectively. Moreover, the hydrogen bonding capability of ionic liquids was a factor affecting the extraction process with considering anions.…”

Section: Extraction Mechanism Analysismentioning

confidence: 99%

Application of Ionic Liquid as a Green Solvent for Polyphenolics Content Extraction of Peperomia pellucida (L) Kunth Herb

Ahmad

Yanuar²,

Mulia³

et al. 2017

JYP

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“…26 Ethyl acetate was chosen because they have hydrogen bonding interaction with trans-resveratrol and water molecules, resulting in the trans-resveratrol and water migrating to the organic solvent from the ionic liquid. 15 The miscibility of IL with water also had a positive influence on recovery analytes and the possibility to regenerate IL by evaporation organic solvent.…”

Section: Discussionmentioning

confidence: 99%

“…10 It makes IL better than organic solvent. IL has good extractability for the various active compounds, such as from Peperomia pellucida, 11 Dioscorea nipponicae, 12 Psidium guajava, Smilax china, 13 Curcuma longa, 14 Apocynum venetum, 15 and Lycium ruthenicum. 16 The IL 1-n-butyl-3-methylimidazolium ([Bmim]Br) solution was well known to extract trans-resveratrol from Polygoni cuspidatum.…”

Section: Introductionmentioning

confidence: 99%

Optimization of Ionic Liquid-Based Microwave Assisted Extraction to Obtain Trans-resveratrol from Gnetum gnemon L. Seeds

Ayuningtyas¹,

Rahmawati²,

Sutriyo³

et al. 2017

JYP

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Introduction: Gnetum gnemon L. (Melinjo) is popular in Indonesia as a source of nutrition. Its seeds contain trans-resveratrol, which has been shown to have multiple pharmacological activities. The application of ionic liquid [Bmim]Br as a selected solvent in the microwave assisted extraction (MAE) method was developed for extraction of trans-resveratrol from Melinjo seeds. MAE method with ionic liquid has also been applied to extract trans-resveratrol from the different plant with a high extraction yield value. Methods: The Box-Behnken design on four factors with response surface methodology were used to optimize extraction conditions for transresveratrol content from Melinjo seeds. For further, the various salt was applied to separate of the trans-resveratrol form ionic liquid and facilitate for extraction back using an organic solvent. Results: The optimum process for the ionic liquid-based microwave assisted extraction was below: [Bmim]Br concentration 2.5 mol/L; liquid-melinjo seeds powder ratio 15 mL/g; microwave power 10%; and extraction time 10 min. Under optimized conditions, the trans-resveratrol value was 1.34 mg/g. Moreover, the salt Na 2 CO 3 0. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

show abstract

Extraction, Preconcentration and Isolation of Flavonoids from Apocynum venetum L. Leaves Using Ionic Liquid-Based Ultrasonic-Assisted Extraction Coupled with an Aqueous Biphasic System

Cited by 53 publications

References 45 publications

Enrichment of the Gamma Oryzanol Level from Rice Bran by Addition of Inorganic Salts on Ionic Liquid 1-Butyl-3- Methylimidazolium Hexafluorophosphate ([BMIM] PF6) Extraction

Enrichment of the Gamma Oryzanol Level from Rice Bran by Addition of Inorganic Salts on Ionic Liquid 1-Butyl-3- Methylimidazolium Hexafluorophosphate ([BMIM] PF6) Extraction

Application of Ionic Liquid as a Green Solvent for Polyphenolics Content Extraction of Peperomia pellucida (L) Kunth Herb

Optimization of Ionic Liquid-Based Microwave Assisted Extraction to Obtain Trans-resveratrol from Gnetum gnemon L. Seeds

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