Extraction, structural properties, and bioactivities of Moringa (Moringa oleifera Lam.) isothiocyanates: A review

Wu, Qi; Zhou, He-Jiang; Sheng, Jun; Su, Ling-Yan; Tian, Yang

doi:10.1016/j.fbio.2023.103447

Food Bioscience

2024

DOI: 10.1016/j.fbio.2023.103447

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Extraction, structural properties, and bioactivities of Moringa (Moringa oleifera Lam.) isothiocyanates: A review

Qi Wu,

He-Jiang Zhou,

Jun Sheng

et al.

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2024

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Cited by 4 publications

References 88 publications

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Preparation and activity study of selenium nanoparticles from polysaccharides of Moringa oleifera leaves

Dong,

Wang,

et al. 2024

Food Measure

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Preparation and activity study of selenium nanoparticles from polysaccharides of Moringa oleifera leaves

Dong,

Wang,

et al. 2024

Food Measure

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Advancements in conventional and supercritical CO2 extraction of Moringa oleifera bioactives for cosmetic applications: A review

Kessler,

Martins,

Manrique

et al. 2024

The Journal of Supercritical Fluids

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Phytochemical Profiling and Molecular Investigation of Moringa Oleifera Lam. Leaves for Anti-Arthritic Potential: Assessment and Identification of Phytopharmaceuticals through GC-MS Analysis, In Silico Study, ADMET Analysis, and In Vitro Evaluation

Mamgain,

Kenwat,

Paliwal

2024

CBIOT

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Background:: The drumstick tree, Moringa oleifera Lam. (family Moringaceae), is known as a magical plant due to its broad pharmacological activities. Traditionally, the leaves of this plant are used for anti-inflammatory action. However, the compounds in Moringa oleifera leaves and their mechanism that showanti-arthritic potential are unknown. Methods:: In this study, a preliminary phytochemical investigation of Moringa oleifera leaves eth-anolic extract was conductedusing qualitative analysis followed by Gas Chromatography-Mass Spectrometry (GC-MS) analysis to determine the constituents in the extracts. Results:: The results indicated the presence of various phytochemical compounds (about 316). Out of these, about 16 compounds were identified that covered 54.63 % of the total ethanolic extract. A molecular docking study was further performed using selected two compounds i.e. 3, 7, 11, 15-tetramethylhexadec-2-en-1-ol and neophytadiene and different targets proteins MMP9 (1L6J), PGE2 (1Z9H), TLR-1-TLR-2 (2Z80), COX-II (3NT1 and 5F19), iNOS (3NW2), HtrA1 (3TJO), JAK-1 (4K6Z), MCSF (5LXF) and TLR-4 (5NAO). Later on, an online tool was used to perform ADME/T analysis of the identified compounds. The DPPH and ABTS assay confirmed the strong potential of this extract for antioxidant activity, which correlates with anti-arthritic potential. Conclusion:: Based on molecular docking, the mechanism for these compounds for the anti-arthritic activity of these magical plant leaves was identified. It is concluded from the study that Moringa oleifera leaves ethanolic extract have potential compounds that may be used to develop more ef-fective formulations for better therapeutic exercise against inflammatory diseases like rheumatoid arthritis.

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Extraction, structural properties, and bioactivities of Moringa (Moringa oleifera Lam.) isothiocyanates: A review

Cited by 4 publications

References 88 publications

Preparation and activity study of selenium nanoparticles from polysaccharides of Moringa oleifera leaves

Preparation and activity study of selenium nanoparticles from polysaccharides of Moringa oleifera leaves

Advancements in conventional and supercritical CO2 extraction of Moringa oleifera bioactives for cosmetic applications: A review

Phytochemical Profiling and Molecular Investigation of Moringa Oleifera Lam. Leaves for Anti-Arthritic Potential: Assessment and Identification of Phytopharmaceuticals through GC-MS Analysis, In Silico Study, ADMET Analysis, and In Vitro Evaluation

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