Extraspinal Musculoskeletal Tuberculosis

Madkour, M. Monir; Kudwah, Aida J. N.; Bagi, Mohammed Abd El

doi:10.1007/978-3-642-18937-1_34

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2016

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“…Skeletal TB is an uncommon form of ExP-TB and affects either the spine (comprising 5% of ExP-TB) or peripheral joints as “osteoarticular TB (OA-TB)” which constitutes a further 5% of ExP-TB. Usually presenting as a chronic monoarthritis, most often affecting the hip, knee, or wrist joint, OA-TB typically has an insidious onset without constitutional symptoms or features of pulmonary TB [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

HIV Infection and Osteoarticular Tuberculosis: Strange Bedfellows

Hodkinson

Osman

Botha-Scheepers

2016

Case Reports in Rheumatology

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We report the case of a 47-year-old female patient with rheumatoid arthritis and HIV infection presenting with a 3-week history of a painful swollen knee, increased serum inflammatory markers, and a low CD4 lymphocyte count. The diagnosis of TB arthritis was made by synovial fluid culture, GeneXpert/PCR, and confirmed by histopathology of a synovial biopsy. A mini literature review suggests that although HIV infection is associated with extrapulmonary TB, osteoarticular TB is a relatively unusual presentation in an HIV positive patient. The diagnostic utility of the GeneXpert test is explored. We also describe the patient's good response to an intra-articular corticosteroid injection in combination with standard anti-TB therapy.

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Section: Discussionmentioning

confidence: 99%