Eye movement abnormalities in somatic tinnitus: Fixation, smooth pursuit and optokinetic nystagmus

Kapoula, Z.; Yang, Q.; Bonfils, P.; Londero, Alain

doi:10.1016/j.anl.2009.10.004

Cited by 13 publications

(11 citation statements)

References 35 publications

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“…Our recent study reported abnormalities of fixation, smooth pursuit and optokinetic nystagmus in 5 cases of such patients [4], particularly deficits for vertical pursuit eye movements and fixation instability for tinnitus patients, which is line with cerebellar dysfunction.…”

Section: Introductionmentioning

confidence: 69%

Central Crosstalk for Somatic Tinnitus: Abnormal Vergence Eye Movements

et al. 2010

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BackgroundFrequent oulomotricity problems with orthoptic testing were reported in patients with tinnitus. This study examines with objective recordings vergence eye movements in patients with somatic tinnitus patients with ability to modify their subjective tinnitus percept by various movements, such as jaw, neck, eye movements or skin pressure.MethodsVergence eye movements were recorded with the Eyelink II video system in 15 (23–63 years) control adults and 19 (36–62 years) subjects with somatic tinnitus.Findings1) Accuracy of divergence but not of convergence was lower in subjects with somatic tinnitus than in control subjects. 2) Vergence duration was longer and peak velocity was lower in subjects with somatic tinnitus than in control subjects. 3) The number of embedded saccades and the amplitude of saccades coinciding with the peak velocity of vergence were higher for tinnitus subjects. Yet, saccades did not increase peak velocity of vergence for tinnitus subjects, but they did so for controls. 4) In contrast, there was no significant difference of vergence latency between these two groups.InterpretationThe results suggest dysfunction of vergence areas involving cortical-brainstem-cerebellar circuits. We hypothesize that central auditory dysfunction related to tinnitus percept could trigger mild cerebellar-brainstem dysfunction or that tinnitus and vergence dysfunction could both be manifestations of mild cortical-brainstem-cerebellar syndrome reflecting abnormal cross-modality interactions between vergence eye movements and auditory signals.

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Section: Introductionmentioning

confidence: 69%

Central Crosstalk for Somatic Tinnitus: Abnormal Vergence Eye Movements

et al. 2010

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“…New insights in the neural basis of tinnitus may be found with the development of animal models and advanced electrophysiological recording techniques to study behavioral assessment and therapeutic compounds to treat tinnitus. Some authors showed that many patients have somatic tinnitus whereby movements manipulations of the eyes, head, neck, jaw and shoulder can modulate the loudness and pitch of their tinnitus [77-82]. These findings may underline the involvement of non auditory centers in the pathogenesis and regulation of tinnitus.…”

Section: Resultsmentioning

confidence: 99%

New Trends in Tinnitus Management

Fioretti

Eibenstein²,

Fusetti³

2011

TONEUJ

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Tinnitus is a perception of sound in absence of sound stimulation. Tinnitus in many cases cannot be eliminated by conventional medical treatment with drugs or surgery. Some people who begin to notice tinnitus, whether spontaneous or induced by noise, trauma or other insult, will experience spontaneous resolution, but many patients will have persistent tinnitus. For some of them, tinnitus sensation will be joined by tinnitus suffering, with many adverse effects like anxiety, depression and sleep disorders. For these tinnitus sufferers the psychological and acoustic approach proposed by the Tinnitus Retraining Therapy and Acoustic Desensitization Protocol may be helpful. Periodically new treatments are suggested like low-frequency repetitive transcranial magnetic stimulation and sequential phase shift sound cancellation treatment based on the frequency and loudness matching of the tinnitus. The aim of this work is to review modern considerations for the treatment of tinnitus.

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“…Many recent studies reported eye movement abnormalities in tinnitus patients (e.g., Mezzalira et al, 2007; Kapoula et al, 2010; Yang et al, 2010). Kapoula et al (2010) pointed out abnormalities in fixation, smooth pursuit, and optokinetic nystagmus in a few cases.…”

Section: Discussionmentioning

confidence: 99%

“…Kapoula et al (2010) pointed out abnormalities in fixation, smooth pursuit, and optokinetic nystagmus in a few cases. In a more extensive study, they reported specific abnormalities in vergence eye movements, particularly in divergence, and abnormal interactions between saccade and vergence (Yang et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

“…Interestingly, recent studies demonstrated that ST could impair oculomotor performance both during fixation, smooth pursuit, and optokinetic nystagmus movements (Coad et al, 2001; Jozefowicz-Korczynska and Pajor, 2002; Mezzalira et al, 2007; Kapoula et al, 2010; Lockwood et al, 2011), and also in vergence movements (Yang et al, 2010). To our knowledge, quantitative studies of saccades in ST patients have not yet been done, leaving alone the possible differences between right and left sided tinnitus.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Differential auditory-oculomotor interactions in patients with right vs. left sided subjective tinnitus: a saccade study

Lang¹,

Yang²,

Orssaud³

et al. 2013

Front. Hum. Neurosci.

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Subjective tinnitus (ST) is a frequent but poorly understood medical condition. Recent studies demonstrated abnormalities in several types of eye movements (smooth pursuit, optokinetic nystagmus, fixation, and vergence) in ST patients. The present study investigates horizontal and vertical saccades in patients with tinnitus lateralized predominantly to the left or to the right side. Compared to left sided ST, tinnitus perceived on the right side impaired almost all the parameters of saccades (latency, amplitude, velocity, etc.) and noticeably the upward saccades. Relative to controls, saccades from both groups were more dysmetric and were characterized by increased saccade disconjugacy (i.e., poor binocular coordination). Although the precise mechanisms linking ST and saccadic control remain unexplained, these data suggest that ST can lead to detrimental auditory, visuomotor, and perhaps vestibular interactions.

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Eye movement abnormalities in somatic tinnitus: Fixation, smooth pursuit and optokinetic nystagmus

Cited by 13 publications

References 35 publications

Central Crosstalk for Somatic Tinnitus: Abnormal Vergence Eye Movements

Central Crosstalk for Somatic Tinnitus: Abnormal Vergence Eye Movements

New Trends in Tinnitus Management

Differential auditory-oculomotor interactions in patients with right vs. left sided subjective tinnitus: a saccade study

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