Fabrication and a detailed study of antibacterial properties of α-Fe₂O₃/NiO nanocomposites along with their structural, optical, thermal, magnetic and cytotoxic features

Abstract

Nanomaterials have specific properties which are uncommon in their bulk counterparts. Because of these unique characteristics, nanotechnology has been explored for various applications by the scientific community and it can play a crucial role in providing solutions of current major healthcare problems. In the present work, we describe the fabrication of a novel inorganic alternative of traditional antibiotics, which can effectively counter the pathogenic bacteria including multi drug resistant bacterial strains. For this purpose, nanocomposites of Fe/Ni oxide with different molar concentrations of nickel have been prepared via wet-chemical approach along with the α-Fe2O3 and NiO nanoparticles. The bactericidal efficiency of the prepared samples were tested against pathogenic strains of B. subtilis, S. aureus, E. coli and S. typhi using two distinct methods. In addition to this, structural, physical and chemical properties of the nanomaterials were studied using XRD, TEM, EDAX, Raman, VSM and TGA-DTA. Also, the cytotoxicity of synthesized samples was assessed using MTT assay against human cell lines MCF-10A (normal) and MCF7 (cancer).

In situ Raman spectroscopy reveals the structure evolution and lattice oxygen reaction pathway induced by the crystalline–amorphous heterojunction for water oxidation

“…16,17 The peaks at 481 cm À1 , 565 cm À1 and 692 cm À1 belong to the vibration peaks of NiO. 16,18 Specically, the Raman peak at 481 cm À1 represents the vibration peak of NiO defects, indicating that there are abundant oxygen defects in amorphous NiO. This result is also consistent with the EPR measurement.…”

“…1h, the Raman peaks at 204 cm À1 , 287 cm À1 and 326 cm À1 belong to the vibration peaks of A 1g and E 2g in a-Fe 2 O 3 , respectively. 16,17 The peaks at 481 cm À1 , 565 cm À1 and 692 cm À1 belong to the vibration peaks of NiO. 16,18 Specically, the Raman peak at 481 cm À1 represents the vibration peak of NiO defects, indicating that there are abundant oxygen defects in amorphous NiO.…”

A Bifunctional Photo‐Assisted Li–O2 Battery Based on a Hierarchical Heterostructured Cathode

“…[35] Additionally, the Raman spectrum of TF/CC ( Figure 2d) also displays the characteristic vibration peaks of α-Fe 2 O 3 at 289 cm −1 for the A 1g mode, 410 cm −1 for the E g mode, and 1318 cm −1 from the two-magnon scattering of α-Fe 2 O 3 nanorods. [36,37] The remaining obvious peaks at 141, 232, 447, and 608 cm −1 match with peaks of TiO 2 / CC, and correspond to be the vibration modes of rutile TiO 2 . [34] Also, the intensity of the D band and G band from the pristine CC are significantly suppressed, due to the dense coverage of the dendrite-like structure on the carbon fibers.…”

A Comparative Analysis of the Antibacterial Spectrum of Ultrasmall Manganese Ferrite Nanozymes with Varied Surface Modifications

“…fluorescens . Additionally, various nanocomposites such as Fe/Ni oxide, Fe/Zn oxide, Fe/Cu oxide, α-Fe 2 O 3 /Co 3 O 4, and α-Fe 2 O 3 /MnO have demonstrated notable antibacterial activity against S. typhi, E.…”