Fabrication and characterization of core-shell gliadin/tremella polysaccharide nanoparticles for curcumin delivery: Encapsulation efficiency, physicochemical stability and bioaccessibility

Zhang, Xiaomin; Wei, Zihao; Wang, Xin; Wang, Yuming; Tang, Qingjuan; Huang, Qingrong; Xue, Changhu

doi:10.1016/j.crfs.2022.01.019

Cited by 30 publications

(10 citation statements)

References 45 publications

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“…Especially under 8 h ultraviolet radiation, the retention rate of Cur in FG–COS–Cur nanoparticles were remain above 80%. A similar situation was also observed in previous researches ( Zhang et al, 2022 ). The improved photostability of Cur might be due to the antioxidant effect of FG-COS conjugates, which prevented the UV-induced loss of hydrogen protons of Cur ( Cai et al, 2021 ).…”

Section: Resultssupporting

confidence: 92%

Development of fish gelatin-chitooligosaccharide conjugates through the Maillard reaction for the encapsulation of curcumin

Lin

Cai²,

Chen³

et al. 2022

Current Research in Food Science

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Section: Resultssupporting

confidence: 92%

Development of fish gelatin-chitooligosaccharide conjugates through the Maillard reaction for the encapsulation of curcumin

Lin

Cai²,

Chen³

et al. 2022

Current Research in Food Science

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“…The Z-average diameter of 7S-150-Cur was 84.37 nm, significantly higher than that of 7S-Cur (75.11 nm) due to the attachment of dextran in the 7S-150 nanoparticles. The value of PDI <0.3 suggests that the particles exhibited a relatively ideal dispersity [ 31 ]. As illustrated in Table 2 , the PDI value of 7S-Cur and 7S-150-Cur were 0.24 and 0.27, respectively, lower than 0.30, indicating that the nanocomplexes all exhibited a homogeneous size distribution.…”

Section: Resultsmentioning

confidence: 99%

Glycated Soy β-Conglycinin Nanoparticle for Efficient Nanocarrier of Curcumin: Formation Mechanism, Thermal Stability, and Storage Stability

Wang

et al. 2022

Foods

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In this study, soy β-conglycinin (7S) was glycated with dextran of different molecular masses (40, 70, 150, 500 kDa) by the dry-heating method to synthesize soy β-conglycinin-dextran (7S-DEX) conjugates. The curcumin (Cur) loaded nanocomplexes were prepared based on 7S-DEX conjugates by a pH-driven self-assemble strategy to enhance the solubility and thermal stability of curcumin. Results showed that the 7S-150 conjugates (glycated from 7S with dextran (150 kDa)) could remain stable in the pH 3.0–pH 8.0 range and during the heat treatment. The results of fluorescence quenching and FT-IR indicated that glycated 7S were combined with curcumin mainly by hydrogen bonding and hydrophobic interaction, and 7S-150 conjugates had higher binding affinity than natural 7S for curcumin. The loading capacity (μg/mg) and encapsulation efficiency (EE%) of 7S-150-Cur were 16.06 μg/mg and 87.51%, respectively, significantly higher than that of 7S-Cur (12.41 μg/mg, 51.15%). The XRD spectrum showed that curcumin was exhibited in an amorphous state within the 7S-150-Cur nanocomplexes. After heating at 65 °C for 30 min, the curcumin retention of the 7S-150-Cur nanocomplexes was about 1.4 times higher than that of free curcumin. The particle size of 7S-150-Cur nanocomplexes was stable (in the range of 10–100 nm) during the long storage time (21 days).

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“…The reason for this was that the isoelectric point of BSA is approximately 4.7, and the solution was easy to coagulate and flocculate near the isoelectric point. The more it deviated from the isoelectric point, the more stable the solution was [ 34 ].…”

Section: Resultsmentioning

confidence: 99%

The Loading of Epigallocatechin Gallate on Bovine Serum Albumin and Pullulan-Based Nanoparticles as Effective Antioxidant

Wang

Zhang

et al. 2022

Foods

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Due to its poor stability and rapid metabolism, the biological activity and absorption of epigallocatechin gallate (EGCG) is limited. In this work, EGCG-loaded bovine serum albumin (BSA)/pullulan (PUL) nanoparticles (BPENs) were successfully fabricated via self-assembly. This assembly was driven by hydrogen bonding, which provided the desired EGCG loading efficiency, high stability, and a strong antioxidant capacity. The encapsulation efficiency of the BPENs was above 99.0%. BPENs have high antioxidant activity in vitro, and, in this study, their antioxidant capacity increased with an increase in the EGCG concentration. The in vitro release assays showed that the BPENs were released continuously over 6 h. The Fourier transform infrared spectra (FTIR) analysis indicated the presence of hydrogen bonding, hydrophobic interactions, and electrostatic interactions, which were the driving forces for the formation of the EGCG carrier nanoparticles. Furthermore, the transmission electron microscope (TEM) images demonstrated that the BSA/PUL-based nanoparticles (BPNs) and BPENs both exhibited regular spherical particles. In conclusion, BPENs are good delivery carriers for enhancing the stability and antioxidant activity of EGCG.

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Fabrication and characterization of core-shell gliadin/tremella polysaccharide nanoparticles for curcumin delivery: Encapsulation efficiency, physicochemical stability and bioaccessibility

Cited by 30 publications

References 45 publications

Development of fish gelatin-chitooligosaccharide conjugates through the Maillard reaction for the encapsulation of curcumin

Development of fish gelatin-chitooligosaccharide conjugates through the Maillard reaction for the encapsulation of curcumin

Glycated Soy β-Conglycinin Nanoparticle for Efficient Nanocarrier of Curcumin: Formation Mechanism, Thermal Stability, and Storage Stability

The Loading of Epigallocatechin Gallate on Bovine Serum Albumin and Pullulan-Based Nanoparticles as Effective Antioxidant

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