Fabrication of a highly sensitive adenosine aptasensor based on covalent attachment of aptamer onto chitosan-carbon nanotubes-ionic liquid nanocomposite

Covalent attachment of aptamer onto nanocomposite as a high performance electrochemical sensing platform: Fabrication of an ultra-sensitive ibuprofen electrochemical aptasensor

“…Thus, using new transducers to enhance loading Apt onto the surface and to improve sensitivity is the recent trend in the fabrication of electrochemical aptasensors [20]. In the recent years, the combination of Apts with a variety of nanoengineered materials such as carbon nanotubes [21,22], graphene nanosheets [23], their nanocomposite [24,25], and noble metal nanoparticles [26][27][28] are shown for improving the performance of aptasensors. Also, these nanomaterial were applied for the development and fabrication of other biosensors.…”

Chemical sensors based on polymer composites with carbon nanotubes and graphene: the role of the polymer

“…A more complex sensor based on CS, MWCNTs and an ionic liquid has been developed by Shahdost-fard et al 132 They prepared a highly sensitive adenosine aptasensor based on the covalent attachment of an aptamer onto the MWCNT-IL-CS composite. CS improved the dispersion ability of the IL, leading to uniform CNT distribution within the composite.…”

Ultrasensitive electrochemical immunosensor for PSA biomarker detection in prostate cancer cells using gold nanoparticles/PAMAM dendrimer loaded with enzyme linked aptamer as integrated triple signal amplification strategy

“…Up to now, electrochemical immunosensor based on antibodyaptamer, have received great interests because compared to antibodies, aptamers can be easily modified, are smaller in size, are cheaper to produce, and can be generated against a wide array of different target molecules Shahdost fard et al, 2013Shahdost fard et al, , 2014. Furthermore, most aptamers are directly selected against the target analyte and they are more sensitive than their respective targets' antibodies.…”