Bio nanocomposites form a fascinating interdisciplinary area that brings together biology, materials science, and nanotechnology. New bio nanocomposites are impacting diverse areas, in particular, biomedical science. Generally, polymer nanocomposites are the result of the combination of polymers and inorganic/organic fillers at the nanometer scale. The extraordinary versatility of these new materials springs from the large selection of biopolymers and fillers available to researchers. Existing biopolymers include, but are not limited to, polysaccharides, aliphatic polyesters, polypeptides and proteins, and polynucleic acids, whereas fillers include clays, hydroxyapatite, and metal nanoparticles. The interaction between filler components of nanocomposites at the nanometer scale enables them to act as molecular bridges in the polymer matrix. This is the basis for enhanced mechanical properties of the nanocomposite as compared to conventional micro composites. Bio nanocomposites add a new dimension to these enhanced properties in that they are biocompatible and/or biodegradable materials [1]. Along with the existing synthetic polymeric materials, poly (vinyl alcohol) (PVA) has been intensively researched in a myriad of studies ranging from conventional to advanced prospective applications. PVA as a thermoplastic and biocompatible petroleumbased polymer is a water-soluble polymer with many hydroxyl groups pendant in the side chains. It has been studied intensively because it has high hydrophilicity, processability, biocompatibility, good physical and mechanical properties, complete biodegradability, excellent chemical resistance, and a favorable capacity to form a film. These properties have led to its broad industrial use in, for example, medical wrapping membranes, drug delivery, adhesive and thickener materials, filtration