Facial eczema from a sunscreen: <i>Scutellaria baicalensis</i>, a novel allergen beginning to attract attention

Adam, Tania; Bursztejn, Anne‐Claire; Schmutz, J.‐L.

doi:10.1111/cod.13453

Cited by 4 publications

(6 citation statements)

References 4 publications

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“…It has also been studied in contact dermatitis models and showed beneficial effects 5 . Very few cases of allergic contact dermatitis to S. baicalensis have been published, mainly related to Anthelios sunscreen (La Roche Posay, L'Oreal) with reports of three affected patients 6–8 . Only one other case of allergic contact dermatitis to both resveratrol and S. baicalensis has been published in a 49‐year‐old woman using Resveratrol BE cream, like our patient 9 .…”

Section: Discussionmentioning

confidence: 67%

“…and S. baicalensis 0.5% aq. have been tested in healthy patients and showed no positive reaction, confirming the absence of irritation when tested at these concentrations 3–9 …”

Section: Discussionmentioning

confidence: 73%

“…have been tested in healthy patients and showed no positive reaction, confirming the absence of irritation when tested at these concentrations. [3][4][5][6][7][8][9] This case highlights this importance of patch testing all the cosmetics in question brought by the patient, and in case of a positive reaction, to perform an additional patch test with the respective ingredients, in order to identify new emerging allergens.…”

Section: Discussionmentioning

confidence: 91%

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Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product

Badaoui¹

2022

Contact Dermatitis

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Section: Discussionmentioning

confidence: 67%

“…and S. baicalensis 0.5% aq. have been tested in healthy patients and showed no positive reaction, confirming the absence of irritation when tested at these concentrations 3–9 …”

Section: Discussionmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 91%

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Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product

Badaoui¹

2022

Contact Dermatitis

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“…Three cases of topical sensitization to S. baicalensis root extract have been published involving three patients with facial eczema: a 49‐year‐old female using a night cream with resveratrol, baicalein, and vitamin E; a 37‐year‐old female using Anthelios BB cream teintée SPF 50+ sunscreen; and a 53‐year‐old man using Anthelios sunscreen . Patch tests in 15 and 10 controls were performed by Gallo et al and Scheers et al, respectively, with negative results.…”

Section: Discussionmentioning

confidence: 99%

Allergic contact dermatitis to Tinosorb S, Scutellaria baicalensis, and other emerging allergens in cosmetics

et al. 2020

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K E Y W O R D S : abietic acid, case report, contact dermatitis, dehydroabietic acid, hydrocolloid dressing, rosin Colophonium (rosin) is a natural resin derived from pine. It contains numerous chemical compounds, mostly abietic acid and its derivatives. 1,2 CASE REPORTA 13-year-old girl sustained a skin laceration on the left lower leg. She applied an over-the-counter (OTC) hydrocolloid dressing ("Dressing OMURA ET AL.

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“…But the introduction of botanical preparations into cosmetics is an increasing cause of contact dermatitis in patients. There were studies reported that sunscreen containing SB could cause facial inflammation to somebody [ 131 – 133 ]. Therefore, whether SB can be widely used in cosmetics or skin care products still needs further study.…”

Section: Toxicitymentioning

confidence: 99%

Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review

et al. 2020

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Scutellaria baicalensis Georgi. (SB) is a common heat-clearing medicine in traditional Chinese medicine (TCM). It has been used for thousands of years in China and its neighboring countries. Clinically, it is mostly used to treat diseases such as cold and cough. SB has different harvesting periods and processed products for different clinical symptoms. Botanical researches proved that SB included in the Chinese Pharmacopoeia (1st, 2020) was consistent with the medicinal SB described in ancient books. Modern phytochemical analysis had found that SB contains hundreds of active ingredients, of which flavonoids are its major components. These chemical components are the material basis for SB to exert pharmacological effects. Pharmacological studies had shown that SB has a wide range of pharmacological activities such as antiinflammatory, antibacterial, antiviral, anticancer, liver protection, etc. The active ingredients of SB were mostly distributed in liver and kidney, and couldn't be absorbed into brain via oral absorption. SB’s toxicity was mostly manifested in liver fibrosis and allergic reactions, mainly caused by baicalin. The non-medicinal application prospects of SB were broad, such as antibacterial plastics, UV-resistant silk, animal feed, etc. In response to the Coronavirus Disease In 2019 (COVID-19), based on the network pharmacology research, SB’s active ingredients may have potential therapeutic effects, such as baicalin and baicalein. Therefore, the exact therapeutic effects are still need to be determined in clinical trials. SB has been reviewed in the past 2 years, but the content of these articles were not comprehensive and accurate. In view of the above, we made a comprehensive overview of the research progress of SB, and expect to provide ideas for the follow-up study of SB.

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Facial eczema from a sunscreen: Scutellaria baicalensis, a novel allergen beginning to attract attention

Cited by 4 publications

References 4 publications

Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product

Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product

Allergic contact dermatitis to Tinosorb S, Scutellaria baicalensis, and other emerging allergens in cosmetics

Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review

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