Facial skin metastasis due to small-cell lung cancer: a case report

Barbetakis, Nikolaos; Samanidis, George; Paliouras, Dimitrios; Samanidou, Elpida; Tzimorota, Zoi; Asteriou, Christos; Xirou, Persefoni; Tsilikas, Christodoulos

doi:10.1186/1752-1947-3-32

Cited by 15 publications

(21 citation statements)

References 6 publications

(7 reference statements)

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“…There was no patient whose primary site was middle lobe of the lung as observed in our case. (2,6,(9)(10)(11). The rest of the three patients had skin metastases at two or more sites (3,5,10).…”

Section: Discussionmentioning

confidence: 98%

“…Size of skin metastasis was 5-50 mm in diameter (1)(2)(3)(4)(5). Most of them were less than 20 mm in diameter (2,3,5,6,(9)(10)(11). Various shapes were found in skin metastasis such as nodular, inflammatory, and the most lesions were firm, raised, and hemispherical, covered by an intact epidermis, while some patients had ulcerated lesions (2,3,6,8,9).…”

Section: Discussionmentioning

confidence: 99%

“…In the PubMed database, we found 20 cases with skin metastasis from SCLC (1-12). Among them, precise clinical courses were described in 15 cases (2)(3)(4)(5)(6)(8)(9)(10)(11). Table 1 showed the clinical features of SCLC patients with skin metastasis.…”

Section: Discussionmentioning

confidence: 99%

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Skin metastasis from small cell lung cancer

Kurishima¹,

Kagohashi²,

Ohara³

et al. 2014

Tuberk Toraks

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Skin metastasis from small cell lung cancer Patients with skin metastasis always had disseminated metastases in many organs. We herein report an unusual case with skin metas-me tasis from small cell lung cancer (SCLC). The patient was treated with platinum-containing chemotherapy, and the response to o the o therapy was evaluated as partial response. The patient had slowly progressive disease and died of SCLC 16 months after the diagno-ag sis of the diseases. If skin lesions, whether it may be typical or not, are found in SCLC patients, biopsy from the lesion would be ld considered to perform. Although trunk may be the most common sites, it is important to suspect such metastasis occurs in patients ti with SCLC.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Skin metastasis from small cell lung cancer

Kurishima¹,

Kagohashi²,

Ohara³

et al. 2014

Tuberk Toraks

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“…SCLC is fatal and most patients die within one year of presentation, with median survival for extensive stage disease being 6-8 months. 18 SCLC has a tendency to progress rapidly and to metastasize early and extensively. Common metastatic sites include lung, liver, bone, adrenal gland and central nervous system.…”

Section: Discussionmentioning

confidence: 99%

Skin Metastasis in a patient with Small-Cell Lung Cancer

Ussavarungsi

Kim²,

Tijani³

2013

SW Resp Crit Care Chron

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A 64-year-old woman presented with abdominal pain and back pain. Physical examinationrevealed a subcutaneous nodule in the anterior abdominal wall. An ultrasoundguidedbiopsy revealed small cell lung carcinoma (SCLC), and additional workuprevealed extensive stage small cell lung carcinoma with involvement of the left lung andthe abdominal viscera. The patient underwent chemotherapy with a good initial response.Lung carcinoma infrequently metastasizes to the skin. However, these lesions,when present, have important prognostic implications since these patients typicallyrespond poorly to chemotherapy and have a mean survival of about five months. Carefulskin evaluation is essential in the evaluation of patients with possible bronchogeniccarcinoma.

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“…A cutaneous metastatic tumor is relatively rare: the incidence of cutaneous metastasis has been reported to be only 0.7-9% in patients with cancer. [1][2][3][4] Generally, the prognosis for these patients is poor. [5][6][7] Resection of the cutaneous metastasis is therefore not a radical therapy.…”

Section: Introductionmentioning

confidence: 99%

Palliative surgical treatment for cutaneous metastatic tumor is a valid option for improvement of quality of life

Goto

Omodaka

Yanagisawa

et al. 2015

The Journal of Dermatology

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A cutaneous metastatic tumor is relatively rare, and patients with such a tumor usually have a poor prognosis. Even if the metastases can be treated, the treatment cannot improve the prognosis. However, neglecting metastatic lesions sometimes results in a great deterioration of quality of life. Cutaneous metastatic foci are generally treated with chemotherapy and/or radiotherapy. On the other hand, surgical treatment is sometimes chosen for cutaneous metastases. In this study, we analyzed data for 40 patients with cutaneous metastatic tumors who received surgical treatment at Shizuoka Cancer Center between January 2009 and August 2014. Among these cases, lung cancer was the most common primary cancer and the craniocervical region was the most frequent metastatic site. Among the patients who died, the average duration to death after the operation was 186 days. We consider that resection of cutaneous metastatic tumors as palliative therapy is an appropriate therapeutic option if the patient's condition permits resection. Such treatment can improve quality of life for both the patients and their families.

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Facial skin metastasis due to small-cell lung cancer: a case report

Cited by 15 publications

References 6 publications

Skin metastasis from small cell lung cancer

Skin metastasis from small cell lung cancer

Skin Metastasis in a patient with Small-Cell Lung Cancer

Palliative surgical treatment for cutaneous metastatic tumor is a valid option for improvement of quality of life

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