2021
DOI: 10.1039/d1ra06232h
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Facile synthesis and nematicidal activity evaluation of thiophosphinyl amide [(Pz)2P(S)NHR] and thiophosphonyl diamide [(Pz)P(S)(NHR)2] (Pz = 1,3,5-trimethylpyrazole, R = biphenyl derivatives)

Abstract: A series of SDHI (succinate dehydrogenase inhibitor)-like thiophosphinyl amide [(Pz)2P(S)NHR] and thiophosphonyl diamide [PzP(S)(NHR)2] compounds, where Pz = 1,3,5-trimethylpyrazole and N(H)R = derivatives of 2-aminobiphenyl, were synthesized via a facile two-step process. Some of their nematicidal activities towards Meloidogyne incogita are stronger than that of the amide analogue bixafen.

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