Facteurs de progression de la polykystose rénale autosomique dominante (PKAD) : à propos de 283 cas

Raqui, A.; Berrada, S.; Elhoussni, S.; Rhou, H.; Benamar, L.; Bayahia, R.; Ouzeddoun, N.

doi:10.1016/j.nephro.2015.07.377

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“…The average age of our patients was 51.6 ± 16.4 years. RAQUI et al [7] reported an average age of 48.8 ± 16.6 years; N'GUESSAN in 2015 in Côte d'Ivoire [8] had observed in his patients, an average age of 47.5 ± 13.8 years. We observed a sex ratio of 0.8.…”

Section: Discussionmentioning

confidence: 97%

Epidemiological, Clinical and Evolutive Profile of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in Togo

Mawufemo¹,

Yoan²,

Agbeko³

et al. 2018

OJNeph

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Objective: To describe the epidemiological, clinical and evolutionary profile of ADPKD in Togo. Methods: A retrospective descriptive transversal study over a period of 8 years (2011)(2012)(2013)(2014)(2015)(2016)(2017)(2018) which focused on the analysis of patients' records diagnosed with ADPKD. The diagnosis of ADPKD was retained on the basis of the ultrasound criteria of PEI. Results: During the study period, 27 patients had polycystic kidney disease with a prevalence of 0.87%. The average age was 51.6 ± 16.4 years. There were 10 men (37%) and 17 women (63%), a sex ratio (M/F) of 0.58. The concept of family cystic kidney disease was found in 6 (22.2%) patients. The clinical presentations were dominated by arterial high blood pressure, abdominal pain and abdominal mass respectively in 77%, 63% and 63% of cases. Five patients (18.5%) had a glomerular filtration rate (GFR) greater than 90 ml/min, 17 (62.9%) had a GFR < 60 ml/min. All patients (100%) had multiple renal cysts, 16 patients (59.3%) had dedifferentiated kidneys. Six patients (22.2%) had liver cysts, one patient (3.7%) had lithiasis. Genetic was not achieved because of the poor technical platform and the high cost of these tests. Conclusion: ADPKD is common in our department. It appears to be associated with a high rate of chronic renal failure.

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Section: Discussionmentioning

confidence: 97%