Factores predictores de complicaciones infecciosas en el postoperatorio de la nefrolitotomía percutánea

Soriano, L. Lorenzo; Jurado, David; Ardavín, J. Pérez; Alba, A. Budía; Mateu, P. Bahílo; Villa, M. Trassierra; Acón, D. López

doi:10.1016/j.acuro.2018.05.009

Cited by 15 publications

(3 citation statements)

References 24 publications

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“…Another study recorded a significantly higher rate of post-operative sepsis after percutaneous nephrolithotomy (PCNL) in women (OR 7.8, p = 0.001) [33]. Overall, all the studies determined female gender to be a risk factor for developing sepsis post-stone surgery [32][33][34][35][36][37][38].…”

Section: Post-intervention Sepsismentioning

confidence: 96%

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Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review

et al. 2021

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Purpose of Review The prevalence of kidney stones is rising and historically carries a preponderance for males. However, recent evidence has questioned whether this gender gap is closing. The aim of this systematic review was to examine this further as well as evaluate possible underlying causes. Recent Findings Recent evidence confirms the disparity in kidney stone disease between genders is closing. In the modern era, the rise in prevalence among females has been greater, especially in adolescence. Quality of life is also more adversely affected by kidney stone events among females who are also more likely to develop sepsis after endourological surgery. Males, however, are more likely to present with stone events during periods of high ambient temperatures Summary Recent literature demonstrates a temporal change in the disease burden of KSD among men and women. The latter, especially adolescent females, are more likely to develop KSD in their lifetime compared to previous eras. Determining causation is complex and continued research is warranted.

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Section: Post-intervention Sepsismentioning

confidence: 96%

“…Sepsis is the leading cause of KSD-related mortality [31]. Seven studies were identified, which investigated sepsis post-KSD intervention [32][33][34][35][36][37][38]. It has previously been demonstrated that women have higher sepsis rates after ureteroscopy (URS) than men [39].…”

Section: Post-intervention Sepsismentioning

confidence: 99%

Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review

et al. 2021

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“…At present, there is still controversy about the association between diabetes and post-PCNL infection. Some studies believed that there was a connection between them, but some researchers noted that the connection was not obvious 26,27 . Interestingly, from the data, we synthesized their views and found that diabetes did not directly affect the incidence of post-PCNL infection (Supplement Tables S2, S4 and S6), but the results were significant when the risk scores were compared in groups (Fig.…”

Section: Discussionmentioning

confidence: 99%

Predicting and comparing postoperative infections in different stratification following PCNL based on nomograms

Jiang

Guo

Yang

et al. 2020

Sci Rep

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To discuss the mechanisms of infection complications in different degrees after percutaneous nephrolithotomy (pcnL) through predicting and comparing post-pcnL infections based on nomograms, a retrospective cohort study was conducted among 969 cases who underwent PCNL from Dec 5, 2016 to Dec 25, 2017 in Kunming, Yunnan Province. We examined clinical features, urine routine, blood routine, blood biochemistry, imaging studies and operative information and recorded the examination results before surgery for univariate and multivariate logistic regression. We applied receiver operating characteristic curves, calibration curves, accuracy, specificity, sensitivity, positive predictive value and negative predictive value to evaluate and compare the models. Nomograms were used to visualize the different degrees of postoperative infection complications. The risk scores of the three groups were compared by diabetes mellitus distribution. Our results suggest that the more severe the infection is, the more accurate the model predicts and that the occurrence of severe infection mostly is related to the patients' homeostasis. Hence, we developed an online post-PCNL sepsis dynamic nomogram which can achieve visualization and dynamically predict the incidence of sepsis in postoperative patients. Kidney stones, one of the most common urologic diseases, show an upward trend annually 1 , especially in Southwest China where the incidence rate is higher than those in other parts of the country 2. PCNL is used as the standard method in the treatment of upper urinary tract stone > 2 cm 3 with minimal invasion and a faster and higher stone clearance rate 4. However, complications are reported including fever (21.0-32.1%), blood transfusion (11.2-17.5%), extravasation (7.2%) and septicemia (0.3-4.7%) 5. Infection, as a major complication, is graded into fever, systemic inflammatory response syndrome (SIRS), and sepsis according to the severity. Previous studies have reported the risk factors on the severity of infectious complications, such as gender, nephrostomy 6 , preoperative positive urine culture 7 , stone size 8 , age, diabetes mellitus and complex stones 9. Risk factors of SIRS include PCNL operation history, stone size, degree of hydronephrosis, complex stones, preoperative positive urine culture, perfusion pressure, and neurogenic bladder and the use of antibiotics 10-13. Risk factors of sepsis include stone burden, infectious stone, the number of tracts, preoperative positive urine culture, leukopenia, creatinine and operation time 14-17. Nonetheless, most studies only discussed one or two infection outcomes and did not compare similarities and differences of infection concurrency between different degrees in the same samples. In this study, we established models to predict and to study the infection complications of different degrees after PCNL, and compared the differences between the models to illustrate the different infection mechanisms and the clinical significance. Finally, we developed online application to achieve visu...

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Urolithiasis – Therapie und Rezidivprävention unter Berücksichtigung geschlechtsspezifischer Aspekte

2022

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Factores predictores de complicaciones infecciosas en el postoperatorio de la nefrolitotomía percutánea

Cited by 15 publications

References 24 publications

Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review

Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review

Predicting and comparing postoperative infections in different stratification following PCNL based on nomograms

Urolithiasis – Therapie und Rezidivprävention unter Berücksichtigung geschlechtsspezifischer Aspekte

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