“…The most frequent [4,5,7,8,10,14,16,18,22]. The median or mean increase of body weight ranged from 0.99 to 7.8 (median ¼ 5.6) kg (n ¼ 264) [4,5,7,11,14,16,18,19,22,28]. Eighty-five (17.3%) of 492 patients and 89 (30.7%) of 290 developed new onset diabetes [4e11, 14,16,18e28] and new onset exocrine insufficiency [4,5,7,8,14,16,18e23,26] respectively.…”