Factors affecting the stability and equilibria of free radicals. Part 14. Unexpected spin densities in 1-(trifluoroacetyl)-2,2-diarylhydrazyl revealed by nitrogen-15 labeling

Synthesis and Characterization of BHT-Derived tert-Butyl Dendrons

“…Recent efforts in our group to prepare 3,5-di- tert -butyl dendrons ( B ) have proven costly not only in price of starting materials but also because of poor yields in the initial steps as reported in the literature. 6e, The options for functionalizing the methyl group of 3,5-di- tert -butyltoluene in the preparation of dendron B include oxidation or radical bromination; these reactions, however, proved problematic. The oxidation route 8 gives low yields, while over-bromination is a problem when NBS bromination conditions are employed 6e.…”

“…6e, 8 The options for functionalizing the methyl group of 3,5-di-tert-butyltoluene in the preparation of dendron B include oxidation or radical bromination; these reactions, however, proved problematic. The oxidation route 8 gives low yields, while over-bromination is a problem when NBS bromination conditions are employed. 6e We sought to overcome these limitations.…”