Factors Associated with Atopic Dermatitis and Allergic Rhinitis among Residents of Two Municipal Areas in South Korea

Abstract

Background and Objectives: The growing burden and deleterious health consequences of allergic diseases, especially of allergic rhinitis (AR) and atopic dermatitis (AD), in developed countries remains an important public health issue. The current study aimed to assess the prevalence and to identify the risk factors of atopic dermatitis and allergic rhinitis among residents of Pohang-Si and Yeongdeok-Gun, two municipal areas in South Korea. Materials and Methods: A cross-sectional study was conducted in both municipal areas between 12 November and 13 December 2017. A total of 302 subjects were recruited from 100 households (25 apartments and 25 houses in each municipality), by system extraction according to district code numbers. Data were collected using International Study of Asthma and Allergies in Childhood (ISAAC) Standard Questionnaires for children and a health questionnaire for adults. Risk factors were identified by multivariate logistic regression analysis. Results: Of the 302 study participants, 12.9% and 25.5% had AD and AR, respectively. The significant factors associated with AD by multivariate logistic regression analysis were age ≥19 years (aOR (adjusted odds ratio) 6.9; 95% CI (confidence interval) (2.9–16.37)), residence in Pohang-Si (aOR 2.5; 95% CI (1.18–5.53)), and family history of allergic disease (aOR 2.3; 95% CI (1.09–4.9)). Similarly, the significant factors associated with AR were male gender (aOR 2.3; 95% CI (1.24–4.42)), age ≥19 years (aOR 4.4; 95% CI (2.28–8.48)), residence in Pohang-Si (aOR 2.8; 95% CI (1.51–5.37)), and family history of allergic disease (aOR 6.7; 95% CI (3.50–12.82)). Conclusion: The present study shows that age ≥19 years, residence in Pohang-Si, and family history of allergic disease are risk factors for AD and AR, and that, additionally, male gender is a risk factor of AR. Understanding the risk factors of allergic diseases can aid the design and implementation of evidence-specific strategies to reduce the long-standing problems associated with allergic disease.

Intralymphatic Administration of <b><i>Metagonimus yokogawai</i></b>-Extracted Protein Attenuates Experimental Murine Allergic Rhinitis Model

“…Air pollution, climate change, and global warming are factors that underlie the increasing prevalence of allergic diseases, and most of all, urbanization or industrialization has been known to be associated with the higher prevalence of allergic diseases [9]. It is usually explained by the hygiene hypothesis [10, 11], which involves the loss of cellular and humoral immunoregulatory pathways as a result of the adoption of a Western lifestyle and the disappearance of chronic infectious diseases albeit clear mechanistic insights into the process are still unraveled.…”

Validity and Reliability of The Indonesian Version of Patient Allergic Rhinitis Questionnaire and Allergic Rhinitis Prevalence in A Class Of 2018-2019 Medical Students of Universitas Padjadjaran, Indonesia

“…13 However, some studies stated that the prevalence of AR is higher in males and there are fundamental differences between females and males in the inflammatory pathway towards allergen, causing AR to occur more often in males than females. 14 Allergic disorders involve important geneenvironmental interactions. 3 One of the AR risk factors is a family history of allergy.…”

“…The genetic contribution to allergic disease is estimated to be greater than 50%. 14 The inheritance of risk alleles in many genes has increased the susceptibility to allergic disease. 3 In this study, AR subjects who had a history of allergy in their parents were higher than those who did not have any history of allergy in their parents.…”

Birth Month And Prevalence Of Atopic Dermatitis In Children Under 3 Years In Antananarivo, Madagascar

“…Is is consistent with previous studies. One study in South Korea found that family atopy was strongly correlated with AD occurrence (OR 2,3 ; CI 95% 1,09-4,9) [16].…”