Montbeliarde is a cattle breed of combined milk and meat performance type, which unlike the other breeds is characterized by several positive features, such as better health, high resistance to mastitis, calving ease and good weight gain. The study involved a population of 163 Montbeliarde cows. In view of the substantial role of the IGF-I/IGF-IR system in growth and development, the aim of this study was to show an association between insulin-like growth factor 1 receptor gene polymorphisms in Montbeliarde cows and birth weight of their offspring. Three single nucleotide polymorphisms within the IGF1R gene were analyzed using PCR-RFLP or ACRS-PCR methods.