Factors Associated With Hepatitis B Vaccination Among Men Having Sexual Relations With Men in Montreal, Quebec, Canada

Dufour, Annie; Remis, Robert S.; Alary, Michel; Otis, Joanne; Mâsse, Benoı̂t; Turmel, Bruno; Vincelette, Jean; Lavoie, René; LeClerc, Roger; Parent, Robert

doi:10.1097/00007435-199907000-00002

Cited by 35 publications

(33 citation statements)

References 22 publications

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“…For this reason, we have analyzed our data specifically to identify factors associated with failure to initiate and complete HBV vaccination. 25 Our finding of a strong association of HBV infection with STD reinforces the importance of timely diagnosis and treatment of STDs and, in particular, genito-ulcerative infections. This will also help to prevent HIV infection.…”

Section: Discussionsupporting

confidence: 68%

Association of hepatitis B virus infection with other sexually transmitted infections in homosexual men. Omega Study Group

2000

Am J Public Health

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OBJECTIVES: This study determined the prevalence and factors associated with hepatitis B virus (HBV) infection among men who have sex with men. METHODS: At the baseline visit of an HIV study among men who have sex with men, we asked about HBV vaccination status and tested for HBV markers. RESULTS: Of 625 subjects, 48% had received at least 1 dose of HBV vaccine. Of 328 unvaccinated men, 41% had 1 or more HBV markers. HBV prevalence increased markedly with age and was associated with many sexual and drug-related behaviors. In a multivariate model, 7 variables were independently associated with HBV infection: ulcerative sexually transmitted diseases (odds ratio [OR] = 10.1; 95% confidence interval [CI] = 2.6, 54); injection drug use (OR = 5.2; 95% CI = 1.2, 26); gonorrhea or chlamydia (OR = 4.0; 95% CI = 1.9, 8.9); sexual partner with HIV/AIDS (OR = 3.6; 95% CI = 1.8, 7.1); 50 or more casual partners (OR = 3.4; 95% CI = 1.6, 7.1); received money for sex (OR = 3.0; 95% CI = 1.2, 7.8); and 20 or more regular partners (OR = 2.5; 95% CI = 1.1, 6.1). CONCLUSIONS: In Montreal, men who have sex with men are at risk for HBV infection, but a substantial proportion remain unvaccinated; new strategies are required to improve coverage. Men who have sex with men and who have a sexually transmitted infection, especially a genito-ulcerative infection, appear to be at particularly high risk for HBV infection.

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Section: Discussionsupporting

confidence: 68%

Association of hepatitis B virus infection with other sexually transmitted infections in homosexual men. Omega Study Group

2000

Am J Public Health

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“…This strategy has several limitations. Risk factors cannot be identified for about 30% of HBV cases (9); there is poor compliance to the HBV vaccine schedule in high risk groups (40,41); and HBV infections occur at early stages of intravenous drug use before individuals are identified as being at risk (31).…”

Section: Prevention Of Nosocomial Transmission Of Hbvmentioning

confidence: 99%

Epidemiology of Hepatitis B in Canada

Zhang¹,

Zou²,

Giulivi³

2001

Canadian Journal of Infectious Diseases and Medical Microbiolog

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OBJECTIVE: To provide a current and comprehensive review of the epidemiology of hepatitis B virus (HBV) in Canada. DATA SOURCES: Published and unpublished epidemiological studies and surveillance reports of the past decade, primarily from Canada were studied. Fifty reports addressing HBV surveillance, incidence and prevalence, transmission-associated risk factors, co-infections, and prevention strategies were reviewed. DATA SYNTHESIS: HBV infection is an important vaccine-preventable infectious disease in Canada. The incidence rate of clinically recognized, acute HBV infection in 1998/1999 was estimated to be 2.3/100,000 people or approximately 700 cases a year. The prevalence of HBV carriers is estimated to be 0.5% to 1.0% of the population, but varies substantially according to population-specific risk factors. Most acute HBV infections are associated with injection drug use or high risk heterosexual activities, but 20% to 30% of acute cases did not report any identified risk factors. Surveillance activities such as the National Notifiable Disease Reporting system provide information regarding trends and risk factors. The primary preventive strategy for HBV consists of universal immunization for preadolescents and/or infants. Other strategies, such as the universal prenatal screening and postnatal immunization, and the prevention of nosocomial acquistion, are also important. The recently described hepatitis B surface antigen (HBsAg) escape mutants may not be detected by current HBsAg test assays, and the existing HBV vaccines may not protect vaccinees from infections by such mutants. CONCLUSION: Ongoing surveillance and research are required to assess risk factors for HBV transmission, evaluate the effectiveness of immunization programs and monitor the impact of HBsAg escape mutants. SOURCES DES DONNÉES :Études épidémiologiques publiées et non publiées et rapports épidémiologiques des dix dernières années principalement au Canada. Cinquante rapports sur l'épidémiologie du HBV, son incidence et sa prévalence, les facteurs de risque de sa transmission, les co-infections et les stratégies de prévention ont été passés en revue. SYNTHÈSE DES DONNÉES : L'infection au HBV est une importante maladie infectieuse qu'il est possible de prévenir au moyen d'un vaccin. Au Canada, l'incidence de l'infection aiguë au HBV cliniquement reconnue en 1998-1999 a été estimé à 2,3/100 000 personnes ou à approximativement 700 cas par année. La prévalence des porteurs du HBV se situerait à 0,5 -1 % dans la population, avec une variation substantielle selon les facteurs de risque. La plupart des infections au HBV aiguës sont associées à l'utilisation de drogues par injection ou à des activités hétérosexuelles à haut risque, mais dans 20 à 30 % des cas aigus aucun facteur de risque n'a clairement pu être identifié. Les mesures épidémiologiques comme le système de maladies à déclaration obligatoire offrent des renseignements sur les tendances ou les facteurs de risque. La principale stratégie préventive contre le HBV est l'immunisation ...

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“…An estimated 6,000 deaths occur annually from these complications per year (Koff, 1999;Schafer & Sorrell, 1999). The U.S. CDC recommend vaccination against HBV for all men who have sex with men (MSM), whether self-identifying as gay, bisexual, or not, (CDC, 1991) a group among whom HBV has been identified as one of the most important sexually transmitted diseases (STD; CDC, 1991;Dufour et al, 1999; Institute of Medicine & Committee on Prevention and Control of Sexually Transmitted Diseases, 1997; Kane, 1995;Kingsley et al, 1990). However, available national epidemiologic data and results from community-based HBV vaccination programs indicate that the majority of gay men are not vaccinated (Institute of Medicine & Committee on Prevention and Control of Sexually Transmitted Diseases, 1997;Kane, 1995;MacKellar et al, 2001).…”

mentioning

confidence: 99%

“…Estimates of the prevalence of previous hepatitis B virus infection in this population range from 5 to 81%; prevalence of HBV surface antigen vary from 1 to 11% (Brook, 1998;Seage et al, 1997). Self-reported vaccination rates among sexually active self-identifying and non-self-identifying gay men are low, ranging from 11 to 48% (Dufour et al, 1999;Kane, 1995;Katz, 1996;Loke, Murray-Lyon, Balachandran, & Evans, 1989;Neighbors, Oraka, Shih, & Lurie, 1999;Rhodes, DiClemente, Yee, & Hergenrather, 2000, 2001aSeage et al, 1997). Unfortunately, little is known about HBV vaccination acceptance among these men that could help guide intervention efforts (Dufour et al, 1999;MacKellar et al, 2001;Neighbors et al, 1999;Rhodes et al, 2000;Rhodes et al, 2001a;Seage et al, 1997;Yuan & Robinson, 1994), and no published scales exist to measure possible latent variable correlates of HBV vaccination among gay men (Rudy Detels, Douglas, Greenland, 2003;Yee and Rhodes, 2002).…”

mentioning

confidence: 99%

Attitudes and Beliefs About Hepatitis B Vaccination Among Gay Men: The Birmingham Measurement Study

Rhodes

Hergenrather

2008

Journal of Homosexuality

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This study was designed to develop reliable and valid quantitative measures of the beliefs and attitudes toward hepatitis B virus (HBV) vaccination among gay men, using a community-based participatory research approach. A convenience sample of 358 gay men was recruited in two gay bars. Exploratory factor analysis performed on the first split-half sample was used to assess the factor structure from five scales measuring beliefs about HBV vaccination. The scales were based on constructs from the health belief model and the social cognitive theory. Confirmatory factor analysis was performed on the remaining half-sample using structural equation modeling. Multivariable analysis further validated the scales. These findings propose standardized measures that may be useful in assessing the beliefs and attitudes of gay men toward HBV vaccination to guide intervention design and evaluation.

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Factors Associated With Hepatitis B Vaccination Among Men Having Sexual Relations With Men in Montreal, Quebec, Canada

Cited by 35 publications

References 22 publications

Association of hepatitis B virus infection with other sexually transmitted infections in homosexual men. Omega Study Group

Association of hepatitis B virus infection with other sexually transmitted infections in homosexual men. Omega Study Group

Epidemiology of Hepatitis B in Canada

Attitudes and Beliefs About Hepatitis B Vaccination Among Gay Men: The Birmingham Measurement Study

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