Factors Associated with Hepatitis B Surface Antigen Seropositivity among Pregnant Women in Kigali, Rwanda: A Cross Sectional Study

Nyamusi, Mochama Monica; M’Imunya, James Machoki; Muvunyi, Claude Mambo; Habtu, Michael

doi:10.4172/2471-9846.1000192

Cited by 6 publications

(7 citation statements)

References 36 publications

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“…In contrast it is lower than in studies conducted among rural women in China 9.51%, 44 Yemen 10.8%, 45 Kenya 9.3%, 12 and Gambia 9.2%. 26 However, a slightly lower prevalence was reported in other studies, 3.8% in Tanzania, 25 3.1% in Kigali, 13 and 3.2% in Eritrea. 11 Lower HBsAg prevalence was reported in Japan and Kashan, Isfaha which were 0.5% and 1.56%, respectively.…”

Section: Discussionmentioning

confidence: 56%

“…10 According to different studies, HBV infection among pregnant women in Central and East African countries was 3.2% in Eritrea,9.3% in Kenya, 3.1% in Kigali, and 7.5% in Sudan. [11][12][13][14] Prevalence of hepatitis B is high in Africa, which may be due to low timely birth dose vaccine coverage. The first birth dose vaccine coverage was estimated to be only 3% in low-income countries.…”

Section: Introductionmentioning

confidence: 99%

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Sero-prevalence and associated factors of hepatitis B virus among pregnant women in Hawassa city public hospitals, Southern Ethiopia: Cross-sectional study design

et al. 2022

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Objective: This study aimed to determine the prevalence and identify associated factors of hepatitis B virus infection among pregnant women attending antenatal care (ANC) follow-up. Methods: An institution-based cross-sectional study was conducted from March 04 to April 03, 2020. A total of 381 women were selected using systematic random sampling after every two consecutive women. Structured and interviewer administered questionnaire was used to collect the data. A 2 ml of venous blood sample was drawn from each participant. The plasma was separated from the collected blood samples and was analyzed using a rapid hepatitis B surface antigen (HBsAg) kit to determine hepatitis sero status. Data were entered into the EPI-Data version 3.1, then exported to the statistical package for social sciences version 25 software and analyzed. Multivariable logistic regression was performed to identify independent predictors of HBsAg B seroprevalence at a p-value <0.05. Results: The prevalence of HBsAg sero-positivity among pregnant women was 6.6%, 95% CI (4.2, 8.9). History of hosptal admission (adjusted odds ratio (AOR) = 4.11; 95% CI = 1.33–12.71), surgical history (AOR = 6.8; 95% CI = 1.93–23.93), history dental procedures (AOR = 4.93; 95% CI = 1.31–18.53), and body tatoo practices (AOR = 6.822; 95% CI = 1.89–24.69) were found to be associated with HBsAg sero-positivity. Conclusion: This study found that HBsAg sero positivity among pregnant women in the study area was in intermediate edemicity. Factors such as history of hospital admission, history of surgery, history of dental procedures, and body tattoo practices were found to be associated with HBsAg sero-positivity. The government of Ethiopia should strengthen screening of all pregnant women for HBV as a part of routine ANC in ANC clinics and treating if they are positive to prevent mother to child transmission.

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Section: Discussionmentioning

confidence: 56%

Section: Introductionmentioning

confidence: 99%

Sero-prevalence and associated factors of hepatitis B virus among pregnant women in Hawassa city public hospitals, Southern Ethiopia: Cross-sectional study design

et al. 2022

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“…Similar findings were reported in Khartoum, Bahir Dar, Harar City, and Jigjiga 3,12,36,38 . Contradictory results of surgical procedures in the past were not predictors of HBV infection among pregnant women in Saudi Arabia and Kigali, Rwanda 39,40 . This can be attributed to poor prevention practices during the surgical procedure and lack of proper sterilization of surgical instruments.…”

Section: Discussionmentioning

confidence: 93%

Sero-prevalence of hepatitis B virus and associated factors among pregnant women attending antenatal care in Bosaso general hospital, Puntland, Somalia 2023: A cross-sectional study design

Ahmed,

Ibrahim,

Yusuf

et al. 2024

J. Drug Delivery Ther.

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Background: Hepatitis is an inflammation of the liver caused by a variety of infectious and non-infectious agents, leading to a range of health problems. Hepatitis B virus (HBV) can cause both acute and chronic liver disease, and the most common virus that can be transmitted from mother to child and other modes of transmission are contact with blood or other body fluids during sexual intercourse, unsafe injections, or exposure to sharp instruments. Objective: To determine the seroprevalence and associated factors of HBV infection among pregnant women attending the Antenatal Clinic at Bosaso General Hospital, Puntland, Somalia, in 2023. Methods: A cross-sectional study was conducted among 302 pregnant women who underwent routine ANC at Bosaso General hospital from March 15 to May 15. Study participants were interviewed using a structured questionnaire. A systematic random sampling technique was used to identify participants. Data entry, editing, and cleanup of the collected data were performed by the principal investigator using EPI data, and data analysis was performed using SPSS software version 20 to examine the association between each independent variable and the outcome variable. Bivariate and multivariate logistic regression analyses were performed to determine associations. Result: A total of 302 respondents participated in the study, with a response rate of 96.8%. The overall prevalence of hepatitis B infection among pregnant women was 6.6% (95% CI = 4.0–9.8). Having a history of dental procedures (AOR = 5.52, 95% CI = 1.190–25.68), a history of blood transfusion (AOR = 5.02, 95% CI = 1.088–23.19), a history surgical procedure (AOR = 4.7, 95% CI = 1.014–21.76), or having a family history of HBV infection (AOR = 10.07, 95% CI = (1.27–79.63) were significant predictors of HBV infection among pregnant women. Conclusion: The seroprevalence of HBV was intermediate (2–8%) in the study area according to WHO classification. A history of dental procedures, blood transfusion, surgical procedures, and a family history of hepatitis B virus infection were significantly associated with HBV infection. Keywords: Sero-prevalence; Bosaso; hepatitis B virus; pregnant women.

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“…The result of this study was relatively high when compared to the result reported from Addis Ababa at 3.7%, 20 7.8% Southern Ethiopia, 30 Gandhi memorial hospital at 2.3%, 31 Agena health center in the Gurage zone at 4.1%, 32 Uganda at 2.1% 33 , and Rwanda 3.1%. 34 The variation might be due to the differences in cultural practices and strategies used for infection prevention and risky behavior practices. In comparison with other studies done outside African region, the result of the study was higher than the result reported by Pakistan at 2.78%, 35 Turkey at 2.1%, 36 and India at 1.6%.…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of Hepatitis B Virus Infection and Associated Factors Among Pregnant Women Attending Antenatal Care At Public Hospitals in Borena Zone, Southern Ethiopia

Kampe

Abbai

Tilahun

et al. 2023

Health Services Research and Managerial Epidemiology

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Background Hepatitis B virus (HBV) is one of the major threats to global health, affecting millions of people each year and causing morbidity and mortality. The risk of acquiring chronic HVV infection varies with age, with 90% of infections acquired during the perinatal period. Despite many studies, there is little evidence of this virus in the Borena Zone. Objectives This study was done to assess seroprevalence HBVinfection and associated factors among pregnant women attending antenatal care at selected Borena Zone public hospitals from June 1 to September 30, 2022. Methods A cross-institutional study was conducted on 368 randomly selected pregnant women who received antenatal care at Yabelo General Hospital and Moyale Primary Hospital. Data on sociodemographic and HBV-related factors were collected using a structured questionnaire. A 5 mL blood sample is then taken and tested using a diagnostic method, the enzyme-linked immunosorbent assay. Finally, data were entered using Epidata version 3.1 and exported to SPSS version 25 and Stata version 14 for analysis. Independent predictors were identified using logistic regression analysis and P < .05 was considered statistically significant. Results The prevalence of HBV infection was 21 (5.7%) (95% confidence interval [CI], 3.74-8.61). History of hospitalization (adjusted odds ratio [AOR] = 3.44, 95% CI, 1.07-11.09), traditional tonsillectomy (AOR = 4.16, 95% CI, 1.29-13.40), history of sexually transmitted infection (AOR = 5.99, 95% CI, 1.81-19.85), human immunodeficiency virus (HIV) (AOR = 8.28, 95% CI, 1.66-41.41), and alcohol drinking (AOR = 5.08, 95% CI, 1.49-17.31) were independent predictors of HBV infection. Conclusions The results of this study indicate a moderate prevalence of HBV in selected public hospitals in the Borena Zone. History of hospitalization, traditional tonsillectomy, sexually transmitted infections, HIV, and alcohol use was significantly associated with HBV infection. Therefore, there is a need to conduct health education and more community-based research on disease transmission routes.

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Factors Associated with Hepatitis B Surface Antigen Seropositivity among Pregnant Women in Kigali, Rwanda: A Cross Sectional Study

Cited by 6 publications

References 36 publications

Sero-prevalence and associated factors of hepatitis B virus among pregnant women in Hawassa city public hospitals, Southern Ethiopia: Cross-sectional study design

Sero-prevalence and associated factors of hepatitis B virus among pregnant women in Hawassa city public hospitals, Southern Ethiopia: Cross-sectional study design

Sero-prevalence of hepatitis B virus and associated factors among pregnant women attending antenatal care in Bosaso general hospital, Puntland, Somalia 2023: A cross-sectional study design

Seroprevalence of Hepatitis B Virus Infection and Associated Factors Among Pregnant Women Attending Antenatal Care At Public Hospitals in Borena Zone, Southern Ethiopia

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