Factors associated with improving success rates with gamete intrafallopian transfer under thin-needle spinal anesthesia

Abstract

GIFT can be performed with relative safety under thin needle spinal anesthesia with high implantation and delivery rates if care is made to optimize sperm and equipment preparation. GIFT under thin-needle spinal anesthesia may be an attractive alternative for treatment of longstanding nontubal infertility in couples willing to take the risk of ovarian hyperstimulation and multiple pregnancy.

Anesthesia practices in the united states common to in vitro fertilization (IVF) centers

“…Some anesthetic drugs (propofol, nitrous oxidel and midazolam) have been shown to be toxic to gametes and/or embryos in vitro (5)(6)(7)(8). Toxicity tests on mouse and human oocytes and/or embryos and investigations of follicular fluid and/or serum concentrations have been done (9,10).…”