Factors associated with mortality due to SARS-CoV-2 in the population over 75 years of age in the Community of Madrid

Analysis of infectious diseases care in Spanish hospitals from 2016 to 2020, including the first year of the SARS-CoV-2 pandemic

“…One hundred of every one 100,000 inhabitants over 15 years of age are admitted due to infection as the primary diagnosis each year. In addition, many patients are elderly (more than 40% are over 74 years of age), have stays that exceed one week, and the mean cost is over 3000 euros per admission, with high comorbidity 14 and the presence of associated disease. These subjects therefore would benefit from care by staff with more general training, able to also manage the rest of the patient problems 1 .…”

“…The records generated by clinicians in our hospitals 15 confirm this situation. In that year, patient severity and mortality were high, with an initial mortality rate of 20% and a large proportion of individuals of advanced age and with multiple disease conditions 14 . This warrants the adoption of a general approach.…”

Factors associated with mortality of elderly people due to COVID-19: Protocol for systematic review and meta-analysis

“…However, despite its indiscriminate nature, the elderly population has experienced concentrated mortality since the onset of the pandemic. This demographic, for various reasons, is more vulnerable to complications and fatalities caused by the SARS-CoV-2 virus [ 1 , 2 ].…”

“…The physiological aspects of aging contribute to the vulnerability of the elderly population, impacting the effectiveness of the immune system and increasing susceptibility to morbidity and mortality from infectious diseases [ 3 ]. Moreover, numerous studies indicate that various factors influence the progression and outcome of COVID-19 in the elderly, differing from other age groups [ 1 , 4 , 5 ].…”

“…Specifically, studies in various countries and regions have identified advanced age, male gender, and the presence of comorbidities as the primary biological factors associated with COVID-19 mortality in the elderly [ 1 , 6 ]. Common comorbidities such as hypertension, diabetes, cardiovascular and respiratory diseases, and dementia are strongly linked to increased severity and subsequent mortality from COVID-19 [ 3 , 6 , 7 ].…”