Factors associated with stroke among adult patients with hypertension in Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia, 2018: A case-control study

Abstract

Background Globally, the burden of stroke is increasing at an alarming rate. Factors associated with stroke among hypertensive patients are not consistent across different studies and there are limited studies particularly to hypertensive stroke in the particular setting. This study aimed to assess factors associated with stroke among patients with hypertension in Ayder Comprehensive Specialized Hospital, Mekelle, Tigray, Ethiopia, in 2018. Methods Hospital-based case-control study was conducted from February to April 2018. Cases were adult hypertensive patients with stroke and controls were adult hypertensive patients without a stroke. Cases and controls were identified from the patient's card review. Using a systematic random sampling technique 89 cases and 356 controls were included in this study. Record review, physical measurement, and interview techniques were used to collect data. Data was entered and analyzed by using SPSS version 23. Variables with a p-value of less than 0.25 in the bivariate logistic regression were selected for multivariable logistic regression. The adjusted odds ratio and 95% confidence interval were used to determine the association. P-value <0.05 was used to declare statistical significance. Results The mean age of cases and controls were 56.3 years (SD±13.53) and 51.9 years (SD

Clinical Characteristics, Treatment Outcomes, and its Predictors Among Hospitalized Stroke Patients in Ambo University Referral Hospital, West Ethiopia: A Retrospective Hospital-Based Study

“…Upon multivariable backward logistic regression, those study participants with a history of substance abuse had almost three times higher (AOR=2.839, P=0.024) probability of poor treatment outcome than those who had not. This finding was in line with the studies in northern Ethiopia 29,42 that reported the significant association of social history with poor treatment outcome. Besides, those patients who did not receive stroke medication during admission had at least twelve times higher likely hood of poor treatment outcomes than their counterparts (AOR=12.503, P≤0.001).…”

Analysis of prevalence and influencing factors of stroke in elderly hypertensive patients: Based on the screening plan for the high-risk population of stroke in Jiading District, Shanghai

“…Our study found that dyslipidemia, atrial fibrillation, lack of exercise, and family history of stroke were independent influencing factors for stroke in hypertensive population. Lack of exercise and dyslipidemia have also been shown to be significantly related to the prevalence of stroke in hypertensive patients in some studies, which is consistent with our findings [ 19 , 20 ]. In addition, several studies have reported that alcohol consumption, excessive salt intake, uncontrolled blood pressure, high carotid artery diameter and plaque may all be risk factors for stroke in hypertensive population [ 19 – 22 ].…”

The burden of stroke and modifiable risk factors in Ethiopia: A systemic review and meta-analysis

“…The number of participants in each study ranged from 73 to 503. The most retrieved studies (n = 8) were from Oromia [ 29 – 36 ] followed by Addis Ababa (n = 7) [ 37 – 43 ], Amhara (n = 7) [ 44 – 50 ], Tigray region (n = 4) [ 51 – 54 ], and Southern Nations Nationalities and People’s (SNNP) (n = 1) [ 55 ].…”

“…Out of 27 studies, 21 (77.78%) studies received a low risk of bias. 5 studies [ 29 – 31 , 36 , 39 , 44 , 49 , 51 , 55 ] had a high risk of case definition, five studies [ 29 , 30 , 35 , 45 , 55 ] had random selection bias, and 14 studies [ 29 , 33 – 35 , 39 , 41 , 46 , 47 , 51 , 53 , 56 ] had a high risk of representation bias ( S2 Table ).…”