Factors associated with the acceptance of mass drug administration for the elimination of lymphatic filariasis in Agusan del Sur, Philippines

Amarillo, Maria Lourdes E.; Belizario, Vicente Y.; Sadiang-abay, Jewel T; Sison, Stephanie Anne M.; Dayag, Ariane Marie S

doi:10.1186/1756-3305-1-14

Cited by 50 publications

(71 citation statements)

References 5 publications

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“…In the Philippines and India the perceived benefit of the MDA was associated with compliance. Knowledge of LF was found to be linked to MDA compliance in the Philippines and in Haiti [27],[29]. A KAP survey conducted in Haiti in 2000 as well as follow-up survey in 2004 found that women were more likely to be noncompliant [29].…”

Section: Discussionmentioning

confidence: 99%

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A Community-Based Study of Factors Associated with Continuing Transmission of Lymphatic Filariasis in Leogane, Haiti

et al. 2010

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Seven rounds of mass drug administration (MDA) have been administered in Leogane, Haiti, an area hyperendemic for lymphatic filariasis (LF). Sentinel site surveys showed that the prevalence of microfilaremia was reduced to <1% from levels as high as 15.5%, suggesting that transmission had been reduced. A separate 30-cluster survey of 2- to 4-year-old children was conducted to determine if MDA interrupted transmission. Antigen and antifilarial antibody prevalence were 14.3% and 19.7%, respectively. Follow-up surveys were done in 6 villages, including those selected for the cluster survey, to assess risk factors related to continued LF transmission and to pinpoint hotspots of transmission. One hundred houses were mapped in each village using GPS-enabled PDAs, and then 30 houses and 10 alternates were chosen for testing. All individuals in selected houses were asked to participate in a short survey about participation in MDA, history of residence in Leogane and general knowledge of LF. Survey teams returned to the houses at night to collect blood for antigen testing, microfilaremia and Bm14 antibody testing and collected mosquitoes from these communities in parallel. Antigen prevalence was highly variable among the 6 villages, with the highest being 38.2% (Dampus) and the lowest being 2.9% (Corail Lemaire); overall antigen prevalence was 18.5%. Initial cluster surveys of 2- to 4-year-old children were not related to community antigen prevalence. Nearest neighbor analysis found evidence of clustering of infection suggesting that LF infection was focal in distribution. Antigen prevalence among individuals who were systematically noncompliant with the MDAs, i.e. they had never participated, was significantly higher than among compliant individuals (p<0.05). A logistic regression model found that of the factors examined for association with infection, only noncompliance was significantly associated with infection. Thus, continuing transmission of LF seems to be linked to rates of systematic noncompliance.

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Section: Discussionmentioning

confidence: 99%

“…The picture is similar in other areas of the world. Recent studies in the Philippines and the Colombo district of Sri Lanka found noncompliance rates of 30% and 28% [27],[28]. However, it is important to distinguish between noncompliance for a single or several MDA rounds and systematic noncompliance (never taking a drug for LF).…”

Section: Discussionmentioning

confidence: 99%

A Community-Based Study of Factors Associated with Continuing Transmission of Lymphatic Filariasis in Leogane, Haiti

et al. 2010

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“…Knowledge on LF and perceived benefits of antifilarial drugs were found to be associated with MDA acceptance ( P = 0.08). [11]…”

Section: Discussionmentioning

confidence: 99%

Mass drug administration for elimination of lymphatic filariasis: Recent experiences from a district of West Bengal, India

2013

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Background:Annual mass drug administration (MDA) with diethyl carbamazine (DEC) and Albendazole is the most cost-effective strategy to control lymphatic filariasis (LF).Materials and Methods:The aim of the present study was to assess the coverage and the compliance of MDA, to elicit factors that influenced compliance, to document side-effects reported and to assess the awareness of the community regarding the disease and MDA program in Bankura district, West Bengal after 2012 round of MDA. Multistage cluster sampling method was adopted. Total four clusters; three villages and one urban municipality ward were selected. In each cluster, minimum 30 families were randomly selected and the head or any responsible family member was interviewed using a pre-designed, pre-tested schedule after taking written informed consent. Data were compiled and analyzed using SPSS 19.0.Results:Total eligible population was 683 among which 98.8% received both the drugs. About 5% of the recipients took none of the drugs. More than two-thirds of the families took unsupervised dose. Drug compliance rate was significantly lower in urban (90.7%) than in the rural clusters (95.7%) (z = 2.46, P < 0.05). Effective coverage rate was significantly lower in urban than in the rural clusters (87.4% vs. 95.3%; z = 3.57, P < 0.01). Coverage compliance gap was higher in urban (5.7%) than in rural cluster (3.9%). Fear of side-effects was the main reason for non-compliance. Reported side-effects were few, mild, and transient. Around 60% of the surveyed families were aware about the MDA program whereas, 67% of them heard about LF. Only 41% families were provided information, education, and communication in last 15 days before MDA. Major sources of information for the surveyed families were leaflets (20.3%) and poster (9.8%).Conclusions:Widespread rural urban variation in performance status, poor social mobilization activities, lack of supervised dosing, and lack of knowledge of the community about the disease and the program are the major areas of concern.

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“…Increasing the community's level of awareness about the disease and heightening their understanding of the benefits of the drugs and participation in MDA can lead to closure of the knowledgepractice gap, resulting in improved treatment coverage, behavioral change, and better control of schistosomiasis and other NTDs. 7,9,[18][19][20] To evaluate the impact of a health communication campaign for schistosomiasis control in western Kenya, we collected the perceptions of community health workers (CHWs) with regard to its impact on their ability to deliver praziquantel by MDA.…”

Section: Introductionmentioning

confidence: 99%

The Effect of a Health Communication Campaign on Compliance with Mass Drug Administration for Schistosomiasis Control in Western Kenya—The SCORE Project

Omedo¹,

Ogutu²,

Awiti³

et al. 2014

The American Society of Tropical Medicine and Hygiene

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Abstract. Compliance with mass drug administration (MDA) can be affected by rumors and mistrust about the drug. Communication campaigns are an effective way to influence attitudes and health behaviors in diverse public health contexts, but there is very little documentation about experiences using health communications in schistosomiasis control programs. A qualitative study was conducted with community health workers (CHWs) as informants to explore the effect of a health communication campaign on their experiences during subsequent praziquantel MDA for schistosomiasis. Discussions were audio-recorded, transcribed verbatim, translated into English where applicable, and analyzed thematically using ATLAS.ti software. According to the CHWs, exposure to mass media messages improved awareness of the MDA, which in turn, led to better treatment compliance. Our findings suggest that communication campaigns influence health behaviors and create awareness of schistosomiasis control interventions, which may ultimately improve praziquantel MDA.

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Factors associated with the acceptance of mass drug administration for the elimination of lymphatic filariasis in Agusan del Sur, Philippines

Cited by 50 publications

References 5 publications

A Community-Based Study of Factors Associated with Continuing Transmission of Lymphatic Filariasis in Leogane, Haiti

A Community-Based Study of Factors Associated with Continuing Transmission of Lymphatic Filariasis in Leogane, Haiti

Mass drug administration for elimination of lymphatic filariasis: Recent experiences from a district of West Bengal, India

The Effect of a Health Communication Campaign on Compliance with Mass Drug Administration for Schistosomiasis Control in Western Kenya—The SCORE Project

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