Factors associated with the outcome of TOLAC after one previous caesarean section: a retrospective cohort study

Parveen, Shaina; Rengaraj, Sasirekha; Chaturvedula, Latha

doi:10.1080/01443615.2021.1916451

Cited by 13 publications

(13 citation statements)

References 25 publications

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“…Multiple logistic regression analysis showed that induction of labor was positively associated with TOLAC failure. Cohort studies conducted in India and Israel also showed that labor induction was independently associated with failed TOLAC [ 9 , 15 , 23 ]. The rate of IOL was also higher (16.7%) in the VBAC group in Caroline’ study [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…The study examined demographic, obstetric, maternal, and delivery variables. These variables were chosen based on factors that were previously linked to TOLAC in other studies and their availability in our current clinical database [ 9 – 12 , 15 , 16 ]. The demographic variables included age, body mass index in the admission for TOLAC, gravidity, abortion; history of vaginal delivery, gestational weeks at pregnancy termination, estimated birth weight; The clinical factors includes: time from previous CD, indication for previous CD (failed trial of labor) and lower uterine segment (LUS) thickness.…”

Section: Methodsmentioning

confidence: 99%

“…Several factors have been identified that either increase or decrease the likelihood of successful TOLAC, including a previous vaginal delivery, a favorable cervix and obesity [ 9 , 10 ]. A retrospective case–control study focusing on Israeli women aged 40 years and older showed that the presence of gestational diabetes, induction of labor and higher birth weight were associated with failed TOLAC [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

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Outcomes and risk factors for failed trial of labor after cesarean delivery (TOLAC) in women with one previous cesarean section: a Chinese population-based study

He¹,

Dai²,

Wu³

et al. 2022

BMC Pregnancy Childbirth

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Objective To evaluate the outcomes and risk factors for trial of labor after cesarean delivery (TOLAC) failure in patients in China. Methods Consecutive patients who had a previous cesarean delivery (CD) and attempted TOLAC were included from 2014 to 2020. Patients who successfully delivered were classified into the TOLAC success group. Patients who attempted TOLAC but had a repeat CD due to medical issues were classified into the TOLAC failure group. Multiple logistic regression analyses were performed to examine the risk factors for TOLAC failure. Results In total, 720 women who had a previous CD and attempted TOLAC were identified and included. The success rate of TOLAC was 84.2%(606/720). Seven patients were diagnosed with uterine rupture, none of whom underwent hysterectomy. Multiple logistic regression analysis showed that the induction of labor (OR = 2.843, 95% CI: 1.571–5.145, P < 0.001) was positively associated with TOLAC failure, but the thickness of the lower uterine segment (LUS) (OR = 0.215, 95% CI: 0.103–0.448, P < 0.001) was negatively associated with TOLAC failure. Conclusions This study suggested that TOLAC was effective in decreasing CD rates in the Chinese population. The induction of labor was positively associated with TOLAC failure, but the thickness of the LUS was negatively associated with TOLAC failure. Our findings need to be confirmed in larger samples with patients of different ethnicities.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Outcomes and risk factors for failed trial of labor after cesarean delivery (TOLAC) in women with one previous cesarean section: a Chinese population-based study

He¹,

Dai²,

Wu³

et al. 2022

BMC Pregnancy Childbirth

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“…Factors associated with successful VBAC are spontaneous onset of labor, previous successful VBAC, previous history of vaginal birth, previous history of stillbirth and spontaneous rupture of membrane 16 . At gestational age between 37 to completed 39 weeks chance of successful TOLAC was lower among women undergoing induction compared to expectant management 17 .…”

Section: Discussionmentioning

confidence: 99%

Randomized controlled trial comparing efficacy of a combination regime containing two cervical sensitizers (mifepristone + Foley's catheter) versus single agent mifepristone or Foley's catheter for labor induction in women attempting TOLAC at late third trimester with a dead fetus in utero

Dasgupta,

Goswami

et al. 2023

J of Obstet and Gynaecol

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Randomized controlled trial comparing efficacy of a combination regime containing two cervical sensitizers (mifepristone + Foley's catheter) versus single agent mifepristone or Foley's catheter for labor induction in women attempting TOLAC at late third trimester with a dead fetus in utero.AimTo compare efficacy and safety of a new combination regime comprising of two cervical sensitizers used simultaneously with single agents, for labor induction in women attempting TOLAC at ≥34 weeks' gestation with a dead fetus.MethodThis was a multiarm randomized controlled trial (RCT) where participants received one of the three regimes—single agent oral Mifepristone 200 mg, intracervical Foley's catheter (16 Fr size, filled with 40 mL normal saline after intracervical instillation), and combination regime consisting of both used simultaneously. Number of women undergoing vaginal birth within 48 h of induction (VB48) was the primary outcome compared between groups.ResultsVB48 was higher in participants on combination regime in comparison to participants on Foley's catheter (54 vs. 42). Total vaginal births were higher in participants on combination regime compared to both single agents (58 vs. 48 and 44). Duration and dose of oxytocin augmentation was lower in participants on combination regime compared to both single agents. Induction birth interval was short in participants on combination regime compared to those on Foley's catheter. Maternal complications between groups were similar.ConclusionCombination of cervical sensitizers for labor induction in late third trimester among women with dead fetus attempting TOLAC resulted in higher proportion of vaginal births and might reduce risk of scar dehiscence due to requirement of a lower dose of oxytocin for augmentation.

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“…obstetric clinician due to increased risk of failed trial of labor (TOLAC) and uterine rupture [3][4][5][6]. Additionally, several other maternal morbidities such as need for blood transfusion, thromboembolism, and hysterectomy have been reported [7][8][9].…”

mentioning

confidence: 99%

Artificial rupture of membranes as a mode for induction of labor in women with a previous cesarean section- a retrospective cohort study

Dick

Gutman-Ido

Chill

et al. 2022

BMC Pregnancy Childbirth

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Background Induction of labor in women with a previous cesarean section (CS) is associated with increased rates of uterine rupture and failed attempt for vaginal delivery. Prostaglandins use is contraindicated in this population, limiting available options for cervical ripening. Objective To evaluate the efficacy and safety of artificial rupture of membranes (AROM) as a mode of Induction of labor (IOL) in women with a previous cesarean section. Methods A retrospective cohort study conducted in a single tertiary care center between January 2015 and October 2020. Women with one previous cesarean section and a current singleton term pregnancy requiring IOL, with an unfavorable cervix, were included. The primary outcome was a successful vaginal delivery (VBAC); secondary outcomes were rates of chorioamnionitis, uterine rupture and low Apgar score (< 7). Results Of the 665 women who met the inclusion criteria, 492 (74%) did not receive subsequent oxytocin and 173 (26%) did. There were significant differences in the baseline characteristics between these two groups, including maternal age, cervical dilation at presentation, parity, and a history of a previous VBAC. Among women who were induced solely by AROM the rate of a successful TOLAC was higher (81.3% vs 73.9%), total time of IOL was shorter (mean 8.7 h vs.16.1 h) and the risk of chorioamnionitis was lower (7.3% vs 18.4%). When subdividing the women who received oxytocin into early (< 12 h after AROM) vs late (> 12 h after AROM) administration, there were no significant changes in the rates of successful VBAC or of chorioamnionitis. Conclusion AROM as a single mode of IOL in women with a previous CS is a safe and efficient practice with high rates of successful VBAC. When spontaneous labor does not develop, there is no advantage to delay the administration of oxytocin.

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Factors associated with the outcome of TOLAC after one previous caesarean section: a retrospective cohort study

Cited by 13 publications

References 25 publications

Outcomes and risk factors for failed trial of labor after cesarean delivery (TOLAC) in women with one previous cesarean section: a Chinese population-based study

Outcomes and risk factors for failed trial of labor after cesarean delivery (TOLAC) in women with one previous cesarean section: a Chinese population-based study

Randomized controlled trial comparing efficacy of a combination regime containing two cervical sensitizers (mifepristone + Foley's catheter) versus single agent mifepristone or Foley's catheter for labor induction in women attempting TOLAC at late third trimester with a dead fetus in utero

Artificial rupture of membranes as a mode for induction of labor in women with a previous cesarean section- a retrospective cohort study

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