Factors associated with treatment persistence among people with Type 2 Diabetes Mellitus (T2DM) initiating basal insulin – real-world data from Germany

Initiating insulin: How to help people with type 2 diabetes start and continue insulin successfully

“…The lack of success with real‐world insulin therapy is attributable to several factors including interruption and/or discontinuation of therapy. Recent estimates from claims databases in the USA, Japan and Germany found that 18%‐26% of insulin naïve people with type 2 diabetes who started insulin discontinued therapy in the first year, and an additional 15%‐62% had at least one interruption in that year . Many patients may be lost to follow‐up or are reluctant to admit to poor adherence or discontinuation, thus the true extent of problematic insulin persistence is likely to be underestimated.…”

Initiation of Basal Insulin Analog Treatment for Type 2 Diabetes and Reasons Behind Patients’ Treatment Persistence Behavior: Real-World Data from Germany

“…Patients' treatment patterns and their reasons to continue or discontinue insulin may differ in individual countries, due to differences in health-care systems, extent of patient education, support, and other factors [23][24][25]. Therefore, treatment patterns should be explored separately for individual countries, in particular in Germany, where insulin is started earlier and the regimens used are more intensive than in other countries [26].…”

“…To date, little realworld data is available for Germany regarding treatment persistence in patients with type 2 diabetes after initiation of basal insulin, potential reasons associated with these behaviors, and patients' perceived experiences during the insulin initiation period. A recent study evaluating treatment persistence after initiation of basal insulin therapy based on German sickness fund data (2009)(2010)(2011)(2012) found that 25.7 % of patients with type 2 diabetes discontinued their basal insulin during the first treatment year, and 15.1 % of patients had at least 1 interruption for 3 months or more [24].…”