Factors by which global warming worsens allergic disease

Seastedt, Hana; Nadeau, Kari

doi:10.1016/j.anai.2023.08.610

Cited by 15 publications

(2 citation statements)

References 101 publications

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“…Several strategies have been proposed to mitigate the impact of climate change. Physicians can play a pivotal role by educating patients about climate change and actively contributing to reducing both their personal carbon footprint and that of the healthcare sector ( 70 ).…”

Section: Discussionmentioning

confidence: 99%

Air pollution and rhinitis

Rosario,

Urrutia-Pereira,

Murrieta-Aguttes

et al. 2024

Front. Allergy

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Rhinitis arises from either allergic or non-allergic inflammation of the nasal mucosa, characterized by the infiltration of inflammatory cells into the tissue and nasal secretions, along with structural alterations in the nasal mucosa. The pathways through which air pollution affects rhinitis may diverge from those affecting asthma. This article aims to review the effects of diverse air pollutants on the nose, the correlation of climate change and pollution, and how they aggravate the symptoms of patients with rhinitis.

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Section: Discussionmentioning

confidence: 99%

Air pollution and rhinitis

Rosario,

Urrutia-Pereira,

Murrieta-Aguttes

et al. 2024

Front. Allergy

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“…As reported by UN experts in 2023, 2 billion tons of dust and sand enter the atmosphere each year (approximately 25% related to human activities) [ 90 ]. Sand and dust storms are not only a source of PM, O 3 , and CO 2 , but also a vehicle for microorganisms (e.g., bacteria, fungi, and spores) [ 91 ]. Once inhaled, dust particles activate airway dendritic cells, macrophages, and innate lymphoid cells, causing inflammation.…”

Section: Climate Change and The Immune Systemmentioning

confidence: 99%

The Impact of Climate Change on Immunity and Gut Microbiota in the Development of Disease

Rio,

Caldarelli,

Gasbarrini

et al. 2024

Diseases

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According to the definition provided by the United Nations, “climate change” describes the persistent alterations in temperatures and weather trends. These alterations may arise naturally, such as fluctuations in the solar cycle. Nonetheless, since the 19th century, human activities have emerged as the primary agent for climate change, primarily attributed to the combustion of fossil fuels such as coal, oil, and gas. Climate change can potentially influence the well-being, agricultural production, housing, safety, and employment opportunities for all individuals. The immune system is an important interface through which global climate change affects human health. Extreme heat, weather events and environmental pollutants could impair both innate and adaptive immune responses, promoting inflammation and genomic instability, and increasing the risk of autoimmune and chronic inflammatory diseases. Moreover, climate change has an impact on both soil and gut microbiome composition, which can further explain changes in human health outcomes. This narrative review aims to explore the influence of climate change on human health and disease, focusing specifically on its effects on the immune system and gut microbiota. Understanding how these factors contribute to the development of physical and mental illness may allow for the design of strategies aimed at reducing the negative impact of climate and pollution on human health.

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