Factors influencing renal function after liver transplantation. Results from the MOST, an international observational study

Early Allograft Dysfunction After Liver Transplantation Is Associated With Short- and Long-Term Kidney Function Impairment

“…Numerous recipient pre-and post-LT as well as donor related factors have previously been shown to be associated with an increased risk of post-LT AKI and lack of recovery of hepatorenal syndrome (4)(5)(6). In addition, post-LT factors such as calcineurin inhibitor (CNI) use have been linked to post-LT renal dysfunction (1).…”

Renal Dysfunction and Liver Transplantation

“…This formula may be inaccurate and pick up small differences in GFR that are statistically significant but clinically irrelevant. Although GFR calculations often overestimate GFR measurements (Poge et al, 2005), even using the best formulas available, the Cockcroft-Gault equation has been used in many published studies and was widely used in clinical practice (Burra et al, 2009). …”

“…Lebrón Gallardo (2004), Faenza (2006) and Burra (2009), used serum creatinine; Gonwa et al, 2004used pre-LT GFR & Kim et al, 2004 used creatinine clearance. Indeed mortality after LT is affected modestly by the presence of pretransplant acute renal failure (<2-fold increase), but increases markedly (up to 8-fold) in the face of acute renal failure posttransplant (Yalavarthy et al, 2007).…”

“…Also given organ shortage it should be essential to determine which patients will experience progressive and severe renal dysfunction after liver transplantation (Burra et al, 2009). …”

Enfermedad renal crónica en pacientes trasplantados de hígado en el Hospital Pablo Tobón Uribe 2005-2013

“…La ERC es una complicación cada vez más frecuente en los pacientes que reciben un trasplante de hígado debido a la mayor expectativa de vida de estos pacientes (2). Aproximadamente 10% a 20% de los pacientes trasplantados de hígado presentan insuficiencia renal en los primeros cinco años luego del trasplante (3,4), pero puede ser hasta del 45% en el seguimiento a más largo plazo (5)(6)(7)(8)(9)(10)(11). Este amplio rango está dado por las diferentes definiciones que se le han dado en los estudios a la ERC así como a los méto-dos de medición de la creatinina, la técnica para calcular la depuración y condiciones particulares de los pacientes como la masa muscular.…”