Factors that predict the development of hypertension in women with pregnancy induced hypertension

Shopen, Noa; Schiff, Eyal; Koren‐Morag, Nira; Grossman, Ehud

doi:10.1016/j.jash.2015.03.268

Cited by 3 publications

(1 citation statement)

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“…The altered organ function can lead to persistence of hypertension depending on the severity of the endothelial dysfunction even after delivery of the placenta (13). Early interventions tailored at controlling the high blood pressure during the postpartum period may result in reduction in associated morbidity and mortality resulting from this chronic hypertension (20) (21). The aim of the current study was to identify the histological predictors of this persistent hypertension based on the patient's placenta following delivery so as to guide in easy and timely identi cation of those at risk for early initiation of relevant interventions so as to minimize associated complications.…”

Section: Introductionmentioning

confidence: 99%

Predicting Risk of Chronic Hypertension in Women with Preeclampsia Based on Placenta Histology. A Prospective Cohort Study in Cuba.

Byonanuwe

Fajardo

Nápoles³

et al. 2020

Preprint

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Background: Chronic hypertension is one of the major sequelae of preeclampsia with associated long term morbidity and mortality among previously normotensive women diagnosed with preeclampsia. We identified the predictors of developing this complication in women with preeclampsia admitted at the Carlos Manuel de Cèspedes Teaching Hospital in Cuba based on histological assessment of their placenta so as to guide the health care providers in early identification of the patients at risk for timely intervention against this vicious condition. Methods: A three-year prospective cohort study was conducted between March 2017 and March 2020. A cohort of 178 women diagnosed with preeclampsia was recruited and followed up at 12 weeks postpartum for chronic hypertension. Histological studies were done on their placenta following delivery and the respective result forms used to collect the data. Cox’s hazards regression model was applied to estimate the risk using STATA version 14.2.Results: Chorioamnionitis (HR=1.697, 95%CI: 1.443-3.416, p=0.038), villositary infarcts (HR=1.657, 95%CI: 1.264-2.848, p=0.048), intervillositary thrombus (HR=1.529, 95%CI: 1.231-3.197, p=0.020), and endarteritis (HR=1.242, 95%CI: 1.115-1.804, p=0.025) placental lesions were predictive of chronic hypertension at 12 weeks postpartum.Conclusion: Placental histology in women with preeclampsia is key towards improving the ability to diagnose and monitor those likely to develop chronic hypertension before its onset for timely intervention.

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Section: Introductionmentioning

confidence: 99%

Predicting Risk of Chronic Hypertension in Women with Preeclampsia Based on Placenta Histology. A Prospective Cohort Study in Cuba.

Byonanuwe

Fajardo

Nápoles³

et al. 2020

Preprint

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Cardiovascular Complications of Pregnancy

Góngora

Wenger

2015

IJMS

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Pregnancy causes significant metabolic and hemodynamic changes in a woman’s physiology to allow for fetal growth. The inability to adapt to these changes might result in the development of hypertensive disorders of pregnancy (hypertension, preeclampsia or eclampsia), gestational diabetes and preterm birth. Contrary to previous beliefs these complications are not limited to the pregnancy period and may leave permanent vascular and metabolic damage. There is in addition, a direct association between these disorders and increased risk of future cardiovascular disease (CVD, including hypertension, ischemic heart disease, heart failure and stroke) and diabetes mellitus. Despite abundant evidence of this association, women who present with these complications of pregnancy do not receive adequate postpartum follow up and counseling regarding their increased risk of future CVD. The postpartum period in these women represents a unique opportunity to intervene with lifestyle modifications designed to reduce the development of premature cardiovascular complications. In some cases it allows early diagnosis and treatment of chronic hypertension or diabetes mellitus. The awareness of this relationship is growing in the medical community, especially among obstetricians and primary care physicians, who play a pivotal role in detecting these complications and assuring appropriate follow up.

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Assessment of insulin resistant and the related cardio-metabolic factors in overweight-obese women presented with missed abortion, Baghdad, Iraq

et al. 2015

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Factors that predict the development of hypertension in women with pregnancy induced hypertension

Cited by 3 publications

References 0 publications

Predicting Risk of Chronic Hypertension in Women with Preeclampsia Based on Placenta Histology. A Prospective Cohort Study in Cuba.

Predicting Risk of Chronic Hypertension in Women with Preeclampsia Based on Placenta Histology. A Prospective Cohort Study in Cuba.

Cardiovascular Complications of Pregnancy

Assessment of insulin resistant and the related cardio-metabolic factors in overweight-obese women presented with missed abortion, Baghdad, Iraq

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