Failure Rate and Cosmesis of Immediate Tissue Expander/Implant Breast Reconstruction After Postmastectomy Irradiation

Baschnagel, Andrew M.; Shah, Chirag; Wilkinson, J. Ben; Dekhne, Nayana; Arthur, Douglas W.; Vicini, Frank A.

doi:10.1016/j.clbc.2012.09.001

Cited by 67 publications

(36 citation statements)

References 20 publications

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“…19,21,27,28 The long-term effects of radiation therapy include microvascular damage, fibroblast dysfunction, decreased and disorganized collagen deposition, decreased angiogenesis, and decreased wound tensile strength. 29 Some authors have reported an increased risk of implant loss in patients who have had radiation therapy and hormonal therapy on univariate analyses.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction

Wang

Peled

Chin

et al. 2016

Plastic and Reconstructive Surgery

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Section: Discussionmentioning

confidence: 99%

The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction

Wang

Peled

Chin

et al. 2016

Plastic and Reconstructive Surgery

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“…Eight studies (566 patients) reported total complication rates or reconstructive failure rates that ranged from 16-54% and 0-32%, respectively [6,44,47,48,50,[65][66][67]. Six studies (435 patients) demonstrated no increase in the rate of complications or reconstructive failures when compared to cohorts not receiving adjuvant chemotherapy [44,47,48,50,65,67]. In a single study, an increase in reconstructive failure and overall complication rate was noted in 41 patients that had adjuvant chemotherapy [6].…”

Section: Adjuvant Chemotherapymentioning

confidence: 99%

Breast reconstruction and adjuvant therapy: A systematic review of surgical outcomes

El‐Sabawi

Sosin

Carey

et al. 2015

Journal of Surgical Oncology

111

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“…Some studies show an association with overall complications (36) and, especially, capsular contraction (16,37), while other studies have shown no such association (18,(38)(39)(40)(41).…”

Section: The Effect Of Chemotherapy and Hormone Therapy On Breast Recmentioning

confidence: 99%

Patient determinants as independent risk factors for postoperative complications of breast reconstruction

et al. 2017

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being, health-related quality of life and satisfaction (5,7-10).Patients' satisfaction and health-related quality of life are frequently used as parameters for outcome measurement in plastic surgery. Postoperative complications after breast reconstruction are common and affect patient satisfaction.Determining independent risk factors using patient characteristics could be advantageous for patient assessment and counseling. 2.05, 95% confidence interval (CI) 1.25-3.37, P=0.0005], followed by body mass index (BMI) (OR 1.07, 95% CI 1.01-1.13, P=0.017). High BMI was associated with the highest number of late overall postoperative complications (OR 1.06, 95% CI 1.00-1.11, P=0.042), followed by history of radiotherapy (OR 1.66, 95% CI 1.01-2.74, P=0.046). When the risk factors were combined, the risk for postoperative complications rose exponentially.Conclusions: Our results provide evidence that patients should cease smoking and overweight patients should lose weight before undergoing breast reconstruction. Additionally, if the patient has received radiotherapy, the reconstruction method should be carefully chosen. High BMI, history of radiotherapy, and smoking are independent risk factors for many types of both early and late postoperative complications in breast reconstructive surgery. Combining these risk factors multiplies the risk of postoperative complications.

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Failure Rate and Cosmesis of Immediate Tissue Expander/Implant Breast Reconstruction After Postmastectomy Irradiation

Cited by 67 publications

References 20 publications

The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction

The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction

Breast reconstruction and adjuvant therapy: A systematic review of surgical outcomes

Patient determinants as independent risk factors for postoperative complications of breast reconstruction

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