This research as a purpose to know what influence of liquidity and solvency ratio towardprofitability ratio. Sample from this research is four enterprise in Indonesian Stock Exchangeperiod 2007-2016. The data analysis technique used multiple linear regression analysis usingEviews 6.From the results of tests performed showed that liquidity statistically not significantaffect profitability, as indicated by the probability of > 0,05 is 0,6022. Same diffirent withsolvency who were statistically not significantly affect profitability, which is indicated by theprobability of > 0,05 is 0,1273.