Faktor Risiko Potensial Reaksi Kusta Pada Etnis Asli di  Dua Kantong Kusta – Papua

Antonius,; Arisanti, Yuli; Tanjung, Ratna; Mirino, Yunita

doi:10.22435/bpk.v46i4.17

Cited by 2 publications

(2 citation statements)

References 17 publications

(32 reference statements)

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“…Subject characteristics based on the length of illness has average 15 months in the control group and 8 months in the treatment group. These results in line with other studies, which state that the most extended duration of patients suffering from leprosy is within one year, which is 79.5% (Antonius et al, 2018). Research by Nazli et al (2021) reported that the length of leprosy in the group >12 months in their study was 45.7%.…”

Section: Discussionsupporting

confidence: 90%

Effect of Clitoria Ternatea as Adjuvant Therapy on Serum Cortisol Levels in Leprosy Reaction

et al. 2023

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This study was to investigate the effect of using an extract from Clitoria ternatea as adjuvant therapy on the levels of blood cortisol in patient with leprosy reaction. The current investigation is an experimental study designed a single-blind randomized controlled trial comparison between two groups. The control group which received standard prednisolone therapy and the intervention group received standard prednisolone therapy and adjuvant therapy of Clitoria ternatea extract dose 2 g/day for one month. Serum levels of cortisol were measured by ELISA. The average serum level of cortisol decrease in control grup with statistically significant (p=0.008). The average serum level of cortisol increase in treatment grup with statistically significant (p=0.026) similar with average difference of both groups (p=0.02). According to the results of the study, the use of an extract from Clitoria ternatea extract 2 g / day for one month as adjuvant therapy significantly increase the serum cortisol levels in patients with leprosy reaction.

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Section: Discussionsupporting

confidence: 90%

Effect of Clitoria Ternatea as Adjuvant Therapy on Serum Cortisol Levels in Leprosy Reaction

et al. 2023

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“…Reaksi kusta dapat terjadi sebelum, selama, atau setelah pengobatan Multi Drug Therapy (MDT). 6 Reaksi kusta merupakan penyebab terbesar kerusakan saraf pada penderita kusta. Pada reaksi kusta, faktor risiko terjadinya penyakit ini antara lain, umur saat didiagnosis kusta >15 tahun, lama sakit lebih dari 1 tahun, terdapat kelelahan fisik, dan perubahan hidup tertentu pada wanita seperti pubertas, kehamilan, atau menyusui.…”

Section: Pendahuluanunclassified

Karakteristik Pasien Kusta dengan Reaksi dan Tanpa Reaksi Tahun 2018-2021 Di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang

Dzakiyyah,

Rahmatini,

Gustia

2024

JIKESI

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Abstrak Latar Belakang: Kusta adalah salah satu penyakit menular yang dapat menyerang kulit dan saraf tepi dan disebabkan oleh Mycobacterium leprae. Kusta dapat ditularkan melalui cairan tubuh seperti dari mulut dan hidung serta terdapat kontak erat dan dekat dengan pasien kusta. Kusta dapat menyebabkan seseorang menderita suatu reaksi inflamasi yang disebut dengan reaksi kusta. Reaksi kusta jika tidak diobati secara adekuat dapat menyebabkan kecacatan atau disabilitas. Objektif: untuk mengetahui karakteristik pasien kusta dengan reaksi dan tanpa reaksi pada tahun 2018-2021 di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang Metode: Jenis penelitian ini adalah penelitian deskriptif. populasi penelitian ini adalah seluruh pasien yang terdiagnosis kusta dengan reaksi dan tanpa reaksi oleh klinisi di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang dengan jumlah sampel sebanyak 54 orang dari tahun 2018-2021. Hasil: Hasil penelitian didapatkan kasus kusta tanpa reksi terbanyak pada usia lansia, jenis kelamin laki-laki, tipe kusta MB, pemeriksaan BTA positif, dan tidak ada riwayat kontak erat dengan penderita kusta. Selain itu, kasus kusta dengan reaksi kusta terbanyak pada usia remaja, jenis kelamin laki-laki, tipe kusta MB, pemeriksaan BTA positif, tidak ada riwayat kontak erat dengan penderita kusta , tipe reaksi kusta ENL, dan waktu kejadian reaksi setelah MDT. Kesimpulan: Karakteristik pasien kusta dengan reaksi dan tanpa reaksi paling banyak pada kelompok usia remaja dan lansia, jenis kelamin laki-laki, tipe kusta MB, hasil pemeriksaan BTA positif, tidak ada riwayat kontak erat dengan penderita kusta, mengalami reaksi kusta tipe ENL, dan waktu kejadian reaksi setelah MDT. Abstract Background: Leprosy is and infectious disease caused by Mycobacterium leprae which affects the skin and peripheral nerves. Leprosy can caused a person to suffer from an inflammatory reaction called leprosy reaction. If not treated properly, leprosy reaction can lead to deformity or disability. Leprosy still exist in Indonesia and is still an unresolved problem until this day. Objective: This research aimed to determine the characteristics based on age, gender, majority, occupation, place of residence, complications, type of leprosy, AFB test result, history of close contact, type of leprosy reaction, and time of reaction of leprosy patients with and without reactions at the Dermatology and Venereology Polyclinic, RSUP Dr. M. Djamil Padang From 2018-2021. Methods: This study employed descriptive research. the population of this study consists all patients diagnosed leprosy with and without leprosy reaction by doctors with a total sampling methode obtained was 54 people from 2018-2021. Results: Of the 54 people sampled on this study this results showed that the majority of leprosy cases without reaction were found in elderly were 15 people (42,9%), male were 25 people (71,4%), MB type of leprosy were 25 people (71,4%), positive AFB test result were 17 people (48,5%), and patients with no history of close contact with leprosy patients were 31 people (88,6%). Additionally, the majority of leprosy cases with reactions were found in adolscent were 8 people (42,1%), male were 13 people (68,4%), MB type of leprosy, were 18 people (94,7%), positive AFB test result, were 13 people (68,4%), patients with no history of close contact with leprosy patients were 13 people (68,4%), patients with type 2 leprosy reaction (ENL) were 13 people (68,4%), and experiencing the reaction time after MDT were 9 people (47,4%). Conclusion: The majority of leprosy cases without reaction were found in elderly, male, MB type of leprosy, positive AFB test result, and patients with no history of close contact with leprosy patients. Additionally, the majority of leprosy cases with reactions were found in adolscent, male, MB type of leprosy, positive AFB test result, patients with no history of close contact with leprosy patients, patients with type 2 leprosy reaction (ENL), and experiencing the reaction time after MDT. Keyword: Leprosy, Leprosy Reactions, Without Reaction

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Faktor Risiko Potensial Reaksi Kusta Pada Etnis Asli di Dua Kantong Kusta – Papua

Cited by 2 publications

References 17 publications

Effect of Clitoria Ternatea as Adjuvant Therapy on Serum Cortisol Levels in Leprosy Reaction

Effect of Clitoria Ternatea as Adjuvant Therapy on Serum Cortisol Levels in Leprosy Reaction

Karakteristik Pasien Kusta dengan Reaksi dan Tanpa Reaksi Tahun 2018-2021 Di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang

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