False positive 18F-FDG PET/CT due to gynaecomastia

Ramtahalsing, R.; Arens, Anne; Vliegen, Roy F. A.; Teule, G. J. J.; Ende, Piet L.A. van den

doi:10.1007/s00259-006-0263-7

Cited by 11 publications

(4 citation statements)

References 4 publications

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“… 66 – 68 Unilateral nodular gynecomastia with increased FDG uptake may mimic a primary or secondary tumor. 69 When interpreting FDG PET/CT as a staging tool in oncological male patients, one should consider gynecomastia as a possible cause for increased FDG uptake in the breast.…”

Section: Diseases Of the Male Breastmentioning

confidence: 99%

Spectrum of the Breast Lesions With Increased 18F-FDG Uptake on PET/CT

Dong

Wang

et al. 2016

Clinical Nuclear Medicine

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Interpretation of 18F-FDG PET/CT studies in breast is challenging owing to nonspecific FDG uptake in various benign and malignant conditions. Benign conditions include breast changes in pregnancy and lactation, gynecomastia, mastitis, fat necrosis, fibroadenoma, intraductal papilloma, and atypical ductal hyperplasia. Among malignancies, invasive ductal carcinoma and invasive lobular carcinoma are common histological types of breast carcinoma. Rarely, other unusual histological types of breast carcinomas (eg, intraductal papillary carcinoma, invasive micropapillary carcinoma, medullary carcinoma, mucinous carcinoma, and metaplastic carcinoma), lymphoma, and metastasis can be the causes. Knowledge of a wide spectrum of hypermetabolic breast lesions on FDG PET/CT is essential in accurate reading of FDG PET/CT. The purpose of this atlas article is to demonstrate features of various breast lesions encountered at our institution, both benign and malignant, which can result in hypermetabolism on FDG PET/CT imaging.

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Section: Diseases Of the Male Breastmentioning

confidence: 99%

Spectrum of the Breast Lesions With Increased 18F-FDG Uptake on PET/CT

Dong

Wang

et al. 2016

Clinical Nuclear Medicine

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“…A few authors have reported gynecomastia as a possible cause of false-positive imaging on FDG PET-CT studies, which may be considered in cases presenting with FDG uptake in the breast. 8 9 However, given the presence of a soft tissue mass in the breast on CT images coupled with tracer uptake, the possibility of a metastatic deposit or a second primary needed to be excluded. This was done using mammography, US, and ultimately a biopsy.…”

Section: Discussionmentioning

confidence: 99%

Imaging Evaluation of Male Breast Masses with Histopathologic Correlation: A Case Series

Vaidya

Ramani²

2021

Indian J Radiol Imaging

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The male breast can be afflicted with a wide spectrum of benign and malignant masses, similar to the female breast. A systematic radiological evaluation using mammography, ultrasonography, and when appropriate, magnetic resonance imaging, could aid this differentiation and provide clues to the diagnosis. In this article, we present six cases of male breast masses with an emphasis on the role of imaging in characterization and diagnosis.

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“…FDG PET/CT findings of the sclerosing adenosis have been rarely reported. This case indicates sclerosing adenosis can show increased FDG uptake and should be included in the differential diagnosis of focal breast FDG accumulation along with nonmalignant and malignant conditions, including gynecomastia, 9 mastitis, 10 fat necrosis, 10 fibroadenoma, 10,11 intraductal papilloma, 10 atypical ductal hyperplasia, 10 breast carcinoma, 10,12 angiosarcoma, 13 lymphoma, 14,15 and metastasis 13,16 …”

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confidence: 88%