Abstract:Purpose
Radiopharmaceuticals targeting fibroblast activation protein alpha (FAP) are increasingly studied for diagnostic and therapeutic applications. We discovered FAP expression at immunohistochemistry (IHC) in the alpha cells of the Langerhans insulae of few patients. Therefore, we planned an investigation aimed at describing FAP expression in the pancreas and discussing the implications for radioligand applications.
Methods
We retrospectively included 40 patients from 2 institutions (20 pts each) accord… Show more
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