FARESHARE: An Open-source Apparatus for Assessing Drinking Microstructure in Socially Housed Rats

Abstract

Social factors have been shown to play a significant and lasting role in alcohol consumption. Studying the role of social context on alcohol drinking is important to understand the factors that contribute to initiation or maintenance of casual and problematic alcohol use, as well as those that may be protective. A substantial body of preclinical research has shown that social environment such as housing conditions and social rank plays an important role in alcohol consumption and preference, though the extent of these effects have been obfuscated by methodological differences and technical challenges. Robust individual differences in alcohol intake in socially housed animals are difficult to track when animals share a common fluid source. Commercial solutions are prohibitively expensive and are limited by proprietary software and hardware (including caging systems). Here we describe an affordable, open-source solution for tracking fluid consumption in socially housed rats.

A novel mouse home cage lickometer system reveals sex- and housing-based influences on alcohol drinking

“…However, these systems are costly and require specialized housing. Tracking multiple animals in a cage can be performed with implanted radiofrequency identification (RFID) tags, which have been utilized in commercially available systems and by recently developed open-source behavioral devices to identify group-housed mice with video-assisted tracking in an arena (Peleh et al, 2019), mice in specialized housing (Wong et al, 2023), and rats during home cage drinking (Frie & Khokhar, 2024).…”