‘Farmer's Lung’ in Devon

Smyth, J. T.; Adkins, G. E.

doi:10.1016/0041-3879(70)90082-6

Cited by 5 publications

(6 citation statements)

References 0 publications

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“…In a survey of final diagnostic classifications on hospital discharge, 73% of cases of HP were erroneously classified (14). Finally, fluctuations in the prevalence of farmerÕs lung have been related to a greater diagnostic suspicion attributable to ongoing epidemiological surveys (15). The difficulties in establishing the incidence and prevalence of HP are further complicated by geographical variables, including climatic conditions and, in the case of farmerÕs lung, farming practices.…”

Section: Epidemiologymentioning

confidence: 99%

Hypersensitivity pneumonitis

Girard

and

Cormier

2009

Allergy

116

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The first few cases of hypersensitivity pneumonitis (HP) were described in the early 20th century in farmers exposed to moldy hay or straw. As then, HP has been ascribed to multiple inhaled antigens found in a large variety of environmental settings. Hypersensitivity pneumonitis results from an exaggerated immune response, which gives rise to acute infection‐like symptoms or to progressive, sometimes irreversible lung damage. The diagnosis is based on a combination of clinical characteristics of the disease. Clinical diagnostic criteria have recently been published. The immune mechanisms leading to HP are still incompletely understood. Initially, believed to be a classes III and IV immune response, we now have a clearer understanding of the complex inflammatory events involved. These include the release of pro inflammatory cytokines and a decrease in the immune control mechanisms via surfactant, dendritic and T‐regulatory cells. Despite the improved understanding, the treatment and outcome of HP have not changed. Oral corticosteroids remain the only effective drugs and contact withdrawal constitutes the ideal solution. If unchecked, HP can lead to irreversible lung damage in the form of fibrosis or emphysema, respiratory insufficiency and even death.

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Section: Epidemiologymentioning

confidence: 99%

Hypersensitivity pneumonitis

Girard

and

Cormier

2009

Allergy

116

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“…For each subject the nurse filled in a questionnaire and drew a blood sample for precipitin analysis. All selected subjects were visited in the winter months from 15 January to 30 March. We enrolled 387 subjects in 1980 and 501 in 1981.…”

mentioning

confidence: 99%

Factors influencing the development of serum precipitins to farmer's lung antigen in Quebec dairy farmers.

Cormier¹,

Bélanger²,

Durand³

1985

Thorax

101

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“…For example, farmer's lung disease is more common in the early spring when farmers are apt to enter silos to obtain hay for their livestock. 5 However, most exposures and episodes of illness are not seasonally related. The incidence of these diseases, unlike most other lung diseases, is not increased by cigarette smoking.…”

Section: Definitionmentioning

confidence: 99%

“…70 However, advanced abnormalities may not completely reverse and can lead to disability and death. 5,12,39,43,70 There is limited information indicating that certain special masks can protect farmers from developing farmer's lung disease, 72 but it is doubtful if typical face masks can adequately reduce exposure.…”

Section: Therapymentioning

confidence: 99%