Fast Dissolving Films: Brief review on preparation methods, ingredients and technology used

Abstract

The Oral fast dissolving drug delivery system is defined as dissolved or disintegration in few seconds or within a few minutes hold in the mouth without water and swallowing. In recent years oral fast dissolving films is promising drug delivery system due to several advantages for pediatric and geriatric patient who have trouble to swallowing conventional oral dosage types. over few decades fast disintegrating tablets have gained significant attention alternative to conventional tablet and capsule due to good patient compliance FDTs are solid dosage form which is rapidly disintegrate usually in seconds or minutes when placed on the tongue but there are still some changes due to chocking. Oral fast dissolving films is another way to solve this issue, as oral strips have been novel for the past few years and are well accepted by customers for distribution. Nowadays, breath strips, supplements and a variety of personal care items are commonly used by consumers. This review consists of updates on methods, ingredients and different technology used in fast dissolving film.

Untitled

“…The concentration of plasticizers used in the preparation of oral films ranges from 0 to 20% (w/w) of the dry polymer weight. Various plasticizers employed in the formulation of oral films include polyethylene glycol, glycerol, propylene glycol, dimethyl phthalate, dibutyl phthalate, diethyl phthalate, tributyl phosphate, triethyl citrate, acetyl citrate, castor oil, and triacetin43 .…”