Fast dynamic contrast enhanced mr imaging of cervical carcinoma

Vierzen, Pbj Van; Massuger, Lfag; Ruys, S. H. J.; Barentsz, J.

doi:10.1016/s0899-7071(98)00055-2

Cited by 4 publications

(5 citation statements)

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“…The administration of intravenous contrast medium for cervical cancer assessment is not necessary, as it does not lead to a more accurate staging [30]. The nonenhancing parts from the measured tumor may be related to tumor edema, hypovascular, hypoxic or necrotic tissue.…”

Section: Discussionmentioning

confidence: 99%

Multimodal endocavitary ultrasound versus MRI and clinical findings in pre- and post-treatment advanced cervical cancer. Preliminary report.

et al. 2016

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Aims: The aim of this study was to evaluate the use of pre and post-therapy transrectal and transvaginal ultrasonography (TRUS, TVUS) with contrast enhancement and strain elastography compared with clinical examination and magnetic resonance imaging (MRI) in the assessment of advanced stage cervical cancer. Material and methods: This was a prospective study, carried out over a period of nine months on subjects with advanced-stage cervical cancer (stage ≥IIB). All included patients were examined clinically and underwent abdomino-pelvic contrast enhanced MRI and multimodal US examinations (TRUS with strain elastography and contrast enhanced TVUS) at the time of diagnosis and after radiochemotherapy. Tumor size and staging at TRUS and TVUS was compared with the same data obtained by clinical examination and MRI. Pathology was the golden standard. Results: Eight patients accomplished the inclusion criteria. In five cases the tumor stage was identical on clinical and MRI examinations. In all cases parametrial infiltration was diagnosed by all pre-treatment examinations. No significant differences were observed in tumor size between clinical, US and MRI exams either at baseline or post-therapy, in native or post-contrast examinations. The size of the tumor evaluated pre-treatment proved to be significantly smaller post-contrast in both US and MRI examinations compared with the native images. Post-therapy, no significant differences were observed on US measured tumor dimensions when comparing native with post-contrast images. Oppositely, significant smaller dimensions were observed on post-contrast MRI compared with native scans. Conclusions: TRUS is accurate in the estimation of pre-therapy cervical cancer dimension. The post therapy tumor evaluation is better performed with MRI. The use of intravenous contrast agents on both examinations did not improved the accuracy of tumor evaluation pre-or post-therapy.

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Section: Discussionmentioning

confidence: 99%

Multimodal endocavitary ultrasound versus MRI and clinical findings in pre- and post-treatment advanced cervical cancer. Preliminary report.

et al. 2016

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“…Thus, interpretation of images is easier on the earlier phases of contrast medium enhancement. The use of IV contrast medium increases the contrast between the tumour and normal cervical stroma and can improve tumour detection and localization, this is especially useful for small tumours which may be considered for trachelectomy [15]. Van Vierzen et al [15] found that the combination of pre-contrast and post-contrast MR images did not clearly improve staging accuracy (83%).…”

Section: B Use Of Intravenous Contrast Mediummentioning

confidence: 99%

“…However, the addition of fast dynamic contrast-enhanced MRI improved staging accuracy to 91%. The use of dynamic contrast-enhanced MRI also improves the accuracy of assessment of bladder and rectal wall invasion [15]. Furthermore, the use of IV contrast medium is useful in the post-treatment setting to differentiate residual or recurrent tumour from radiation fibrosis [16] as well as presence of fistulae occurring post radiation therapy.…”

Section: B Use Of Intravenous Contrast Mediummentioning

confidence: 99%

Staging of uterine cervical cancer with MRI: guidelines of the European Society of Urogenital Radiology

Balleyguier

Sala

Cunha³

et al. 2010

Eur Radiol

270

199

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Objective: To design clear guidelines for the staging and follow-up of patients with uterine cervical cancer, and to provide the radiologist with a framework for use in multidisciplinary conferences. Methods: Guidelines for uterine cervical cancer staging and follow-up were defined by the female imaging subcommittee of the ESUR (European Society of Urogenital Radiology) based on the expert consensus of imaging protocols of 11 leading institutions and a critical review of the literature. Results: The results indicated that high field Magnetic Resonance Imaging (MRI) should include at least two T2-weighted sequences in sagittal, axial oblique or coronal oblique

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“…DYNAMIC CONTRAST-ENHANCED magnetic resonance imaging (DCE-MRI) has recently emerged as a promising method for both diagnosis (1)(2)(3)(4)(5)(6) and prognosis (7)(8)(9)(10)(11)(12) of cancer. Remarkably, these positive results have been obtained despite considerable variation in both the methods of data acquisition (eg, pulse sequences, acquisition parameters, spatial resolution and coverage) and analysis (eg, visual inspection (2), parametric analysis (9), pharmacokinetic (8) or physiologic (1) modeling).…”

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confidence: 99%