Fat-Grafting Injection for Soft-Tissue Augmentation

Comparative study of autologous fat vs hyaluronic acid in correction of the nasolabial folds

“…Host histiocytes act to remove fat from broken down, nonsurviving, or disrupted cells. These scavenged cells tend to be older, more mature adipocytes. Three months after transfer, zones of cytosteatonecrosis, lipophagic granulomas, lymphocytes, adipocytes, giant multinucleated cells, and new vessels were found.…”

Small Volume Fat Transfer

“…Interest in this technique has grown, especially as lipo‐suction techniques advanced in the early 1980s. In 1990, Nyugen focused on the muscle as an ideal recipient site, 13 and this was picked up by Zaretsky who used fat to augment vocal chord muscle after chord paralysis. This stabilized the vocal chords making them useful again.…”

“…Vita 11 discussed augmentation for the aging hands and Campbell 12 conducted basic research on the effects of mechanical stress on the adipocites and advocated an 18‐gauge or larger needle for fat transfer. In 1989, Chajchir 13 used histologic studies to demonstrate the long‐term survival of fat.…”

Facial Sculpting and Tissue Augmentation

“…Since the variable longevity of contour correction depends on technique, the amount of fat injected, and location, improvements in harvesting, handling, and the injection process may have an impact on positive patient outcomes 22. However, the fact remains that autologous fat grafting demonstrates unpredictable and sometimes temporary results 25,26. Moreover, harvesting and reinjecting fat are both significant procedures that are associated with downtime and the possibility of serious complications.…”

“…22 However, the fact remains that autologous fat grafting demonstrates unpredictable and sometimes temporary results. 25,26 Moreover, harvesting and reinjecting fat are both significant procedures that are associated with downtime and the possibility of serious complications.…”