Fatal blood and tissue concentrations of more than 200 drugs

Mercury fatal intoxication: Two case reports

“…In the two cases here presented, the values found were 0.33 and 0.21 mg/g for brain, 49.9 and 46.6 mg/g for liver, 77.7 mg/g for kidney in Case 2, and 3.27 and 14.6 mg/g for lung. Moreover, these values are similar to those published in cases of mercury fatal intoxication reviewed in Musshoff et al [12]. In the liver, for instance, the value found in Case 1 was 49.9 mg/g wet weight, within the range of those mentioned in the literature (33.2-56 mg/g after oral exposure) [12,20].…”

“…Also, published post-mortem mercury tissue contents are very scarce and the results found in these case studies can constitute a valuable contribute for the evaluation of the distribution of mercury in the human organism [12].…”

Post-mortem cases involving amphetamine-based drugs in the Netherlands

“…The ranges in MDMA and amphetamine concentrations in the DUI cases and the drug related deaths fall within the range of those considered toxic or potentially lethal by various toxicological reviews or tabulated guides (refs. [25][26][27][28][29][30]; see Tables 4 and 5). Furthermore, they also overlap the range in MDMA or amphetamine concentrations in the drug caused cases in this study.…”

Amitriptylinbedingter Herz-Kreislauf-Stillstand

“…Dies erscheint umso bemerkenswerter, als die hier gemessenen Amitriptylinkonzentrationen deutlich über den in der Literatur oftmals als letal beschriebenen Werten lagen. So verlaufen Amitriptylinvergiftungen mit gemessenen Serumkonzentrationen über 2 mg/l vielfach tödlich, jedoch treten bereits Todesfälle bei deutlich niedrigeren Serumspiegeln auf [10].…”