Fatal cor pulmonale caused by pulmonary tumor microembolism in a patient with occult gastric cancer

Corradi, Domenico; Mormandi, Francesca; Tanzi, Giulia; Ricci, Roberto; Bini, Paola; Giuliotti, Sara; Zompatori, Maurizio

doi:10.1016/j.carpath.2006.02.003

Cited by 4 publications

(2 citation statements)

References 17 publications

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“…Pulmonary artery intimal thickening is not a reliable sign of right ventricular hypertrophy [175] or degree of pulmonary hypertension [176]. Examination of the intra-pulmonary vessels should be performed for primary pulmonary hypertensive disease and obstruction of vessels by emboli [177] (including tumor emboli [178,179]) has been described. In disorders of the lungs, such as chronic obstructive airways disease, the disturbance of the pulmonary architecture may be a more important factor than destruction of lung tissue; in bronchiectasis the formation of bronchopulmonary shunts may be important [175].…”

Section: Sudden Cardiac Death: Right Ventricular Pathologymentioning

confidence: 99%

Sudden adult death

Langlois

2009

Forensic Sci Med Pathol

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In the investigation of sudden death in adults, channelopathies, such as long QT syndrome, have risen to the fore in the minds of forensic pathologists in recent years. Examples of these disorders are touched upon in this review as an absence of abnormal findings at postmortem examination is characteristic and the importance of considering the diagnosis lies in the heritable nature of these conditions. Typically, a diagnosis of a possible channelopathy is evoked as an explanation for a 'negative autopsy' in a case of apparent sudden natural death. However, the one potential adverse effect of this approach is that subtle causes of sudden death may be overlooked. The intention of this article is to review and discuss potential causes of sudden adult death (mostly natural) that should be considered before resorting to a diagnosis of possible channelopathy. Nonetheless, it becomes apparent that many of the potential causes of sudden death can have a genetic basis. Thus, it becomes an important consideration that there may be a genetic basis to sudden death that extends beyond the negative autopsy.

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Section: Sudden Cardiac Death: Right Ventricular Pathologymentioning

confidence: 99%

Sudden adult death

Langlois

2009

Forensic Sci Med Pathol

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“…Although the most common cause of PTCE is gastric cancer, few reports describe PTCE as the first clinical manifestation of gastric cancer (6)(7)(8)(9)(10)(11)(12) (6)(7)(8)(9)(10)(11)(12). It should be emphasized that some are young patients of less than 50 years old (6)(7)(8)(9)(10)12 …”

Section: Discussionmentioning

confidence: 99%