Fatal cytophagic panniculitis

Perniciaro, Charles; Winkelmann, R K; Ehrhardt, Dennis R.

doi:10.1016/0190-9622(95)91371-8

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other investigators have also reported negative results for EBV at multiple organ sites from a patient with fatal CHP. 38 In this regard, Craig et al 37 recently suggested that CHP and SPTL may not be identical. …”

Section: Commentmentioning

confidence: 99%

Cytophagic Histiocytic Panniculitis and Subcutaneous Panniculitis-like T-Cell Lymphoma

Marzano¹,

Berti²,

Paulli³

et al. 2000

Arch Dermatol

140

View full text Add to dashboard Cite

Section: Commentmentioning

confidence: 99%

Cytophagic Histiocytic Panniculitis and Subcutaneous Panniculitis-like T-Cell Lymphoma

Marzano¹,

Berti²,

Paulli³

et al. 2000

Arch Dermatol

140

View full text Add to dashboard Cite

“…Moreover, a controversial entity known as cytophagic histiocytic panniculitis (CHP) has been described as an inflammatory disease (also often associated with hemophagocytic syndrome) with possible connection to SCPTCL (193,194). CHP is a disease that has been recognized to have diverse outcomes ranging from indolent to aggressive/fatal clinical courses (193)(194)(195). PCR gene rearrangement studies have recently demonstrated that CHP is likely part of the same clinicopathologic spectrum of SCPTCL, with SCPTCL representing a neoplastic clonal process, while CHP represents pre-malignant lymphoid disease (191,194,196).…”

Section: Subcutaneous Panniculitis-like T-cell Lymphoma (Scptcl)mentioning

confidence: 99%

Molecular etiology of mature T-cell non-hodgkins lymphomas

Evens

Gartenhaus²

2003

Front Biosci

View full text Add to dashboard Cite

T-cell non-Hodgkin's lymphomas (NHL) represent approximately 10-15% of all lymphomas diagnosed in Western countries. Significant progress has been made over the last 2 decades in defining non-random chromosomal abnormalities. Cytogenetic and molecular analyses have enhanced diagnostic capabilities as well as improved classification and prognostication for T-cell NHL. Gamma-delta T-cell receptor (TCR) clonality now represents the more common TCR rearrangement in subcutaneous panniculitis-like T-cell lymphoma (SCPTCL), hepatosplenic T-cell lymphoma (HSTCL), extranodal NK/T-cell lymphoma, nasal type and enteropathy-type intestinal T-cell lymphoma (EITCL). Non-random, recurrent chromosome abnormalities such as isochrome 7 with HSTCL, complex karyotypes with peripheral T-cell lymphoma, not otherwise characterized (PTCL-NOC), trisomies 3 and 5 with angioimmunoblastic lymphoma (AIL) and t(2;5) with systemic anaplastic T-cell lymphoma have been recognized. Furthermore, identification of relevant protooncogenes and tumor suppressor genes involved in the pathogenesis of T-cell NHL such as the NPM/ALK fusion protein, p53, cyclin dependent kinase inhibitors (p15, p16, p21) and EBV as well as their interplay with the various regulatory pathways of cell cycle progression and apoptosis represent potential candidates for molecular-based therapy. This review presents a detailed analysis of the molecular and genetic perturbations present in mature T-cell lymphomas including discussion of how tumor-specific alterations impact on clinical outcome. Future studies in T-cell NHL are likely to provide additional disease-specific chromosomal translocations and molecular alterations with important translational implications.

show abstract

Inflammatory diseases of the subcutaneous fat

Luzar¹,

Calonje²

2012

McKee's Pathology of the Skin

View full text Add to dashboard Cite

Fatal cytophagic panniculitis

Cited by 3 publications

References 0 publications

Cytophagic Histiocytic Panniculitis and Subcutaneous Panniculitis-like T-Cell Lymphoma

Cytophagic Histiocytic Panniculitis and Subcutaneous Panniculitis-like T-Cell Lymphoma

Molecular etiology of mature T-cell non-hodgkins lymphomas

Inflammatory diseases of the subcutaneous fat

Contact Info

Product

Resources

About