Fatores De Risco Associados À Ocorrência Da Leishmaniose Visceral Na Área Urbana Do Município De Campo Grande/MS

Teles, Ana Paula Silva; Herrera, Heitor Miraglia; Ayres, Fábio Martins; Brazuna, Julia Cristina Maksoud; Abreu, U. G. P. de

doi:10.14393/hygeia1129627

Cited by 7 publications

(1 citation statement)

References 6 publications

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“…There are 21 known species of Leishmania pathogenic to man (Akhoundi et al, 2016;2017), of which we will only take into account in this work the ones represented in Graph 1. The incidence of VL is produced by the adaptation of the vector in anthropically modified areas (Teles et al, 2015), configuring one of the biggest public health problems. When left untreated, it is responsible for 95% of mortality (Oliveira, et al, 2020).…”

Section: Focus On Education Academic Research Leishmaniasis In the Co...mentioning

confidence: 99%

Leishmaniasis in the contemporary clinical context and its therapeutics interventions: A review

Chammas,

Reys,

Rabelo

et al. 2024

Focus on Education: Academic Research

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Leishmaniasis is a tropical disease categorized as neglected due to its impact on populations with limited access to resources. It is caused by various species of the parasite Leishmania, belonging to the Trypanosomatidae family within the order Kinetoplastida, and transmitted by sandflies (Phlebotomine sandflies) during the female's blood meal. Several mammal species, which often coexist closely with humans, serve as biological reservoirs. Leishmaniasis manifests in different forms, including cutaneous (CL), diffuse (DCL), mucocutaneous (MCL), visceral (VL), post-kala-azar dermal (PKDL), and mucosal (ML). In this context, our objective is to provide updated information to facilitate access to data for various specialists dealing with this parasitic disease. Simultaneously, we aim to contribute to public education, particularly among populations facing precarious living conditions and challenges in accessing healthcare services in endemic areas. A total of 135 articles on Leishmania were reviewed, sourced from 95 journals. This endeavor serves as a means to identify potential risks and formulate strategies for preventing and mitigating the consequences of leishmaniasis.

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Section: Focus On Education Academic Research Leishmaniasis In the Co...mentioning

confidence: 99%

Leishmaniasis in the contemporary clinical context and its therapeutics interventions: A review

Chammas,

Reys,

Rabelo

et al. 2024

Focus on Education: Academic Research

View full text Add to dashboard Cite

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Presence of anti-Leishmania antibodies in candidates for kidney transplantation

França

Cunha

Oliveira

et al. 2020

International Journal of Infectious Diseases

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Objectives: Visceral leishmaniasis (VL) is a progressive disease that, left untreated, is typically fatal. The purpose of this investigation was to detect Leishmania sp. infection in hemodialysis patients who had received multiple blood transfusions at a private clinic in Campo Grande, Mato Grosso do Sul state, Midwest Brazil. Methods: Fifty randomly selected volunteers were interviewed for collection of demographic, socioeconomic, and epidemiological data. Indirect immunofluorescence (titers positive when !1:40) and rK39 immunochromatographic tests were employed for serological investigation. Results: Males predominated (60%). Age ranged from 20 to 77 years. Most subjects reported being on hemodialysis for at least one year (94%) and 84% were candidates for kidney transplantation, 67% of whom were on the waiting list. Leishmania sp. infection was detected in 32%. Contact with infected dogs was the only variable associated with infection. Conclusions: Under immunocompromised conditions, VL is opportunistic and potentially fatal. Despite existing risks, screening for VL is not performed in asymptomatic donors and recipients. The detection of anti-Leishmania antibodies in these patients reinforces the need for infection screening before immunosuppressive treatment is initiated to reduce not only the risks of VL development and severity, but also mortality rates in cases of reactivation of latent infection.

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Sandflies in an urban area of transmission of visceral leishmaniasis in midwest Brazil

et al. 2016

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The phlebotomine fauna of Campo Grande city, capital of Mato Grosso do Sul state in Brazil, an endemic area for visceral leishmaniasis, has been thoroughly investigated, but all the insect collections were undertaken with automatic light traps. The present study sought to investigate the fauna in this city using Shannon and Disney traps, having human beings and hamsters, respectively, as bait. Both types of traps were installed in forest fragment and peridomiciliary areas in the period from 2007 to 2009. The phlebotomine females were analyzed by PCR for Leishmania identification. Lutzomyia longipalpis was the only species collected in the peridomiciles and rendered a total of 574 specimens with a 5.2:1 male:female ratio. A total of eight species were attracted to the two traps (one of each type) installed in the forest fragment, including: Bichromomyia flaviscutellata, Evandromyia bourrouli, Evandromyia lenti, Lutzomyia longipalpis, Nyssomyia whitmani, Pintomyia christenseni, Psathyromyia bigeniculata, and Sciopemyia sordellii. A total of 143 specimens were collected, Bi. flaviscutellata accounting for 81% and Lu. longipalpis for 1.4% of them. In one female of Lu. longipalpis collected in a Disney trap installed in a peridomicile, Leishmania (Leishmania) infantum DNA was found, thus strengthening the hypothesis that the transmission of leishmaniasis is in fact occurring in the anthropic environment.

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Fatores De Risco Associados À Ocorrência Da Leishmaniose Visceral Na Área Urbana Do Município De Campo Grande/MS

Cited by 7 publications

References 6 publications

Leishmaniasis in the contemporary clinical context and its therapeutics interventions: A review

Leishmaniasis in the contemporary clinical context and its therapeutics interventions: A review

Presence of anti-Leishmania antibodies in candidates for kidney transplantation

Sandflies in an urban area of transmission of visceral leishmaniasis in midwest Brazil

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