Favourable effect of regular intake of fermented milk containing <i>Lactobacillus johnsonii</i> on <i>Helicobacter pylori</i> associated gastritis

Pantoflickova, D.; Corthésy–Theulaz, Irène; Dorta, Gian; Stolte, Manfred; Isler, Patrick; Rochat, Florence; Enslen, Marc; Blum, A. L.

doi:10.1046/j.1365-2036.2003.01675.x

Cited by 106 publications

(101 citation statements)

References 32 publications

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“…The effect is long lasting compared with the relatively short effect of antibiotics [Pantoflickova et al 2003] and this may be due to its impact on the gut barriers and immunity [Vitini et al 2000]. In addition, it is associated with higher eradication rate [Manfredi et al 2012] and probably low recurrence rates.…”

Section: Discussionmentioning

confidence: 99%

Lactobacillus reuteri in management of Helicobacter pylori infection in dyspeptic patients: a double-blind placebo-controlled randomized clinical trial

Emara

Mohamed

Abdel-Aziz

2013

Therap Adv Gastroenterol

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Introduction: The eradication rate of Helicobacter pylori following the standard triple therapy is declining. This study was conducted to test whether the addition of Lactobacillus reuteri to the standard triple therapy improves the eradication rates as well as the clinical and pathological aspects in H. pylori infection. Methods: A total of 70 treatment-naïve patients were randomly assigned into group A (the L. reuteri treated group) and group B (the placebo control group). Patients were treated by the standard triple therapy for 2 weeks and either L. reuteri or placebo for 4 weeks. They were examined by symptom questionnaire, H. pylori antigen in stool, upper endoscopy with biopsies for rapid urease test and histopathological examination before treatment and 4 weeks after treatment. Results: The eradication rate of H. pylori infection was 74.3% and 65.7% for both L. reuteri and placebo treated groups, respectively. There was a significant difference regarding the reported side effects, where patients treated with L. reuteri reported less diarrhea and taste disorders than placebo group. A significant difference within each group was observed after treatment regarding Gastrointestinal Symptom Rating Scale (GSRS) scores; patients treated with L. reuteri showed more improvement of gastrointestinal symptoms than the placebo treated group. The severity and activity of H. pylori associated gastritis were reduced after 4 weeks of therapy in both groups. The L. reuteri treated group showed significant improvement compared with the placebo treated group. Conclusion: Triple therapy of H. pylori supplemented with L. reuteri increased eradication rate by 8.6%, improved the GSRS score, reduced the reported side effects and improved the histological features of H. pylori infection when compared with placebo-supplemented triple therapy.

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Section: Discussionmentioning

confidence: 99%

Lactobacillus reuteri in management of Helicobacter pylori infection in dyspeptic patients: a double-blind placebo-controlled randomized clinical trial

Emara

Mohamed

Abdel-Aziz

2013

Therap Adv Gastroenterol

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“…The effect of an La1-acidified milk (LC-1) administration was studied in 50 H. pylori-positive healthy volunteers who did not receive any antibiotic treatment in a randomized, controlled, double-blind study; the histology and H. pylori density from gastric biopsies obtained before and after 3 and 16 weeks of treatment were evaluated. 50 LC1 decreased the severity and activity of the gastritis (P ¼ 0.04) as well as the density of H. pylori colonization. Interestingly, the thickness of the mucus layer increased during LC1 consumption.…”

Section: Utilization Of Probiotics In Association With Antibiotics Inmentioning

confidence: 95%

Systematic review: are probiotics useful in controlling gastric colonization by Helicobacter pylori?

Gotteland

Brunser

Cruchet

2006

Aliment Pharmacol Ther

222

168

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SUMMARYHelicobacter pylori is a highly prevalent pathogen considered as an aetiological factor for gastroduodenal ulcers, and a risk factor for gastric adenocarcinoma and lymphoma in humans. Most subjects colonized by this micro-organism are asymptomatic and remain untreated. In symptomatic patients, the antibiotic treatment has a high cost and is not 100% effective because of resistance to antibiotics and to moderate patient compliance. This review discusses the role of probiotics as alternative solutions to assist in the control of H. pylori colonization in atrisk populations.The evidence that some strains of Lactobacillus and Bifidobacterium are able to inhibit H. pylori growth through the release of bacteriocins or organic acids, and may also decrease its adhesion to epithelial cells, is reviewed. In addition, probiotics have a possible role in the stabilization of the gastric barrier function and the decrease of mucosal inflammation. Other aspects that are considered are the contribution of probiotics to the healing of the gastric mucosa linked to their antioxidant and anti-inflammatory properties.Clinical trials in colonized adults and children are reviewed, and suggest that probiotics do not eradicate H. pylori but maintain lower levels of this pathogen in the stomach; in combination with antibiotics, probiotics may increase eradication rate and/or decrease adverse effects. Papers suggesting similar effects on H. pylori by foodstuffs such as berry juice and some milk proteins are quoted. Regular intake of these and other dietary products might constitute a low-cost, large-scale alternative solution applicable for populations at-risk for H. pylori colonization.

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“…johnsonii LC1 disminuyó la densidad de H. pylori en pacientes infectados al administrarse durante cuatro meses en leche fermentada y sin emplear antibióticos (Pantoflickova et al, 2003). Otro producto comercial con L. johnsonii LA1 logró interferir en la colonización gástrica por H. pylori aunque no se logró erradicar (Obregón et al, 2003).…”

Section: Lactobacillus Acidophilusunclassified

Caracterización y potencial probiótico de bacterias lácticas aisladas de leche de oveja guirra

Cruz¹,

Milena²

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Esta editorial es miembro de la UNE, lo que garantiza la difusión y comercialización de sus publicaciones a nivel nacional e internacional. © Claudia Milena Amorocho Cruz, 2011Primera edición, 2011 © de la presente edición:Editorial Universitat Politècnica de València www.editorial.upv.es ISBN: 978-84-695-2327-8 Ref. editorial: 5515 Queda prohibida la reproducción, distribución, comercialización, transformación, y en general, cualquier otra forma de explotación, por cualquier procedimiento, de todo o parte de los contenidos de esta obra sin autorización expresa y por escrito de sus autores. CERTIFICAN:Que la tesis doctoral titulada "CARACTERIZACIÓN Y POTENCIAL PROBIÓTICO DE BACTERIAS LÁCTICAS AISLADAS DE LECHE DEOVEJA GUIRRA", que presenta Dña. Claudia Milena Amorocho Cruz para optar al grado de Doctor por la Universidad Politécnica de Valencia, ha sido realizada bajo su dirección y reúne los requisitos adecuados para ser presentada como tesis doctoral ante el tribunal correspondiente para su lectura y defensa.Y para que conste a los efectos oportunos, firman el presente certificado, Agradecimientos Doy gracias a Dios por mi vida y la de cada una de las personas que me han acompañado durante este tiempo, de cada uno de ustedes me llevo gratos recuerdos.Agradezco al Dr. Manuel Hernández por su dirección, apoyo y darme la oportunidad de trabajar en el laboratorio durante esta etapa, a la Dra. Yolanda Moreno por su dirección, enseñanza y dedicación. A Dr. Enrique Hernández por su gentileza. Al Dr. Javier Hernández por su cordialidad. A la Dra. Ma Angeles Castillo por su escucha y generosidad. A la Dra.Ma Antonia Ferrús por su colaboración incondicional. Al Dr. Luis Roig por su atención y pedagogía. A la Dra. Salut por su acogida. A la Dra. Rosa por su ayuda desinteresada. Al Dr.Gonzalo por compartir de su experiencia en el laboratorio y por las dudas que me ayudó a solucionar. A la Dra. Ana G por su franqueza. A la Dra. Ana J por su atención. Al Dr. Rafael por su amabilidad y al Dr. Jorge G por su sinceridad. A Nancy por su buena disposición y ayuda.Del departamento de Bioquímica, agradezco a la Dra. Ma Jesús Ibañez su colaboración y a la Dra. Consuelo por su confianza y cooperación en la última etapa de la investigación.A mis compañeros de laboratorio Veronica Belenguer y Susana por su buena energía y amistad. A Pilar, Rocío, Ana de la Hoz, Myriam, Eyder, Gloria, Paula, Javier, Irene, Lorena, Albert y muchos otros, por cada uno de los buenos detalles.A mis amigos de los buenos y los malos ratos y que llevo en el corazón Juan Pablo, Anicia, S. Francisca, Javier Eduardo, Amanda del Pilar, Nelly Condori, Alejandro, Marcos, Liliana, Daniel, Pilar Angarita, Liliana del Pilar, Claudia Yaneth y Nelly Alvarez por ser tan especiales, bellos y alegrar mi vida con cada uno de los momentos compartidos.A Begoña por su buen ánimo y ternura, a María Sancho por su generosidad. A los hermanos de la Parroquia de San Martín, en especial la cuarta comunidad por compartir el camino de Fé. A mi familia fuente de mi inspiración por...

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Favourable effect of regular intake of fermented milk containing Lactobacillus johnsonii on Helicobacter pylori associated gastritis

Cited by 106 publications

References 32 publications

Lactobacillus reuteri in management of Helicobacter pylori infection in dyspeptic patients: a double-blind placebo-controlled randomized clinical trial

Lactobacillus reuteri in management of Helicobacter pylori infection in dyspeptic patients: a double-blind placebo-controlled randomized clinical trial

Systematic review: are probiotics useful in controlling gastric colonization by Helicobacter pylori?

Caracterización y potencial probiótico de bacterias lácticas aisladas de leche de oveja guirra

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